ReviewGenes, brain, and behavior2012
Translational behaviour-genetic studies of alcohol: are we there yet?
Review in Genes, brain, and behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Adaptation of the 5-choice serial reaction time task to measure engagement and motivation for alcohol in mice.Frontiers in behavioral neuroscience · 2022Article
- Transfer of incentive salience from a first-order alcohol cue to a novel second-order alcohol cue among individuals at risk for alcohol use disorder: electrophysiological evidence.Addiction (Abingdon, England) · 2021Article
- What Is Addiction? How Can Animal and Human Research Be Used to Advance Research, Diagnosis, and Treatment of Alcohol and Other Substance Use Disorders?Alcoholism, clinical and experimental research · 2019Article
- An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.Alcohol (Fayetteville, N.Y.) · 2018Article
- The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.Alcohol (Fayetteville, N.Y.) · 2017Article
- Sex differences in the behavioral sequelae of chronic ethanol exposure.Alcohol (Fayetteville, N.Y.) · 2017Article
- Does Acamprosate Really Produce its Anti-Relapse Effects via Calcium? No Support from the PREDICT Study in Human Alcoholics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Article
- Cross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol.Frontiers in behavioral neuroscience · 2016Article
- Article
- High drinking in the dark mice: a genetic model of drinking to intoxication.Alcohol (Fayetteville, N.Y.) · 2014Review
- Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.Genes, brain, and behavior · 2014Article
- Rodent models of genetic contributions to motivation to abuse alcohol.Nebraska Symposium on Motivation. Nebraska Symposium on Motivation · 2014Review
- Initial subjective reward: single-exposure conditioned place preference to alcohol in mice.Frontiers in neuroscience · 2014Article
- Ethanol Withdrawal-Associated Drinking and Drinking in the Dark: Common and Discrete Genetic Contributions.Addiction genetics · 2012Article
- Locomotor sensitization to EtOH: contribution of β-Endorphin.Frontiers in molecular neuroscience · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In biomedical research, one key stage of translating basic science knowledge to clinical practice is the reconciliation of phenotypes employed for laboratory animal studies with those important for the clinical condition. Alcohol dependence (AD) is a prototypic complex genetic trait. There is a long history of behaviour-genetic studies of AD in both human subjects and various genetic animal models. This review assesses the state of the art in our understanding of the genetic contributions to AD. In particular, it primarily focuses on the phenotypes studied in mouse genetic animal models, comparing them to the aspects of the human condition they are intended to target. It identifies several features of AD where genetic animal models have been particularly useful, and tries to identify understudied areas where there is good promise for further genetic animal model work.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.