ArticlePloS one2012
Major cellular and physiological impacts of ocean acidification on a reef building coral.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 286 citations in OpenAlex.
- Impacts of hypoxic events surpass those of future ocean warming and acidification.Nature ecology & evolution · 2021Pooled it
- Global adaptation to climate change in the twilight zone revealed by shared signals of selection in mesopelagic lanternfishes.bioRxiv : the preprint server for biology · 2026Article
- Strong Symbiodiniaceae Influence on Coral Gene Expression Under Ocean Acidification and Warming.Integrative and comparative biology · 2026Article
- Ocean acidification modulates material flux linked with coral calcification and photosynthesis.Scientific reports · 2025Article
- Thermal and Acidification Gradients Reveal Tolerance Thresholds in Pocillopora acuta Recruits.Molecular ecology · 2025Article
- Acclimation mechanisms of reef-building coral Acropora gemmifera juveniles to long-term COScientific reports · 2025Article
- Conspecific interactions between corals mediate the effect of submarine groundwater discharge on coral physiology.Oecologia · 2025Article
- Seasonal Proteome Variations inProteomes · 2024Article
- Effects of water flow and ocean acidification on oxygen and pH gradients in coral boundary layer.Scientific reports · 2024Article
- Neuromolecular mechanisms related to reflex behaviour inRoyal Society open science · 2024Article
- Lipid Droplets in EndosymbioticPlants (Basel, Switzerland) · 2024Review
- Article
- Genomic signatures suggesting adaptation to ocean acidification in a coral holobiont from volcanic COCommunications biology · 2023Article
- Synergistic and antagonistic interactions of oxybenzone and ocean acidification: new insight into vulnerable cellular processes in non-calcifying anthozoans.Frontiers in physiology · 2023Article
- Combined responses of primary coral polyps and their algal endosymbionts to decreasing seawater pH.Proceedings. Biological sciences · 2021Article
- Regulation of the Coral-Associated Bacteria and Symbiodiniaceae inFrontiers in microbiology · 2021Article
- The Marine GastropodFrontiers in physiology · 2021Article
- New Insights From Transcriptomic Data Reveal Differential Effects of COFrontiers in microbiology · 2021Article
- Caspases from scleractinian coral show unique regulatory features.The Journal of biological chemistry · 2020Article
- Transcriptional analysis reveals physiological response to acute acidification stress of barramundi Lates calcarifer (Bloch) in coastal areas.Fish physiology and biochemistry · 2020Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As atmospheric levels of CO(2) increase, reef-building corals are under greater stress from both increased sea surface temperatures and declining sea water pH. To date, most studies have focused on either coral bleaching due to warming oceans or declining calcification due to decreasing oceanic carbonate ion concentrations. Here, through the use of physiology measurements and cDNA microarrays, we show that changes in pH and ocean chemistry consistent with two scenarios put forward by the Intergovernmental Panel on Climate Change (IPCC) drive major changes in gene expression, respiration, photosynthesis and symbiosis of the coral, Acropora millepora, before affects on biomineralisation are apparent at the phenotype level. Under high CO(2) conditions corals at the phenotype level lost over half their Symbiodinium populations, and had a decrease in both photosynthesis and respiration. Changes in gene expression were consistent with metabolic suppression, an increase in oxidative stress, apoptosis and symbiont loss. Other expression patterns demonstrate upregulation of membrane transporters, as well as the regulation of genes involved in membrane cytoskeletal interactions and cytoskeletal remodeling. These widespread changes in gene expression emphasize the need to expand future studies of ocean acidification to include a wider spectrum of cellular processes, many of which may occur before impacts on calcification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.