ArticleFrontiers in cellular neuroscience2012
Potentials of endogenous neural stem cells in cortical repair.
Article in Frontiers in cellular neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed.
- Development of synthetic modulator enabling long-term propagation and neurogenesis of human embryonic stem cell-derived neural progenitor cells.Biological research · 2023Article
- Phosphatase and Tensin Homology Deleted on Chromosome 10 Inhibitors Promote Neural Stem Cell Proliferation and Differentiation.Frontiers in pharmacology · 2022Article
- Systematic Review of Nicotine Exposure's Effects on Neural Stem and Progenitor Cells.Brain sciences · 2021Review
- Glycyrrhizin Blocks the Detrimental Effects of HMGB1 on Cortical Neurogenesis After Traumatic Neuronal Injury.Brain sciences · 2020Article
- Effect of cerebral dopamine neurotrophic factor on endogenous neural progenitor cell migration in a rat model of Parkinson's disease.EXCLI journal · 2019Article
- Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel.Frontiers in bioengineering and biotechnology · 2019Article
- Protein Kinase C: Targets to Regenerate Brain Injuries?Frontiers in cell and developmental biology · 2019Article
- Grafted Neural Stem Cells Show Lesion-Specific Migration in Radiation-Injured Rat Brains.RSC advances · 2018Article
- Interactions Between Neural Progenitor Cells and Microglia in the Subventricular Zone: Physiological Implications in the Neurogenic Niche and After Implantation in the Injured Brain.Frontiers in cellular neuroscience · 2018Review
- Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid.International journal of molecular sciences · 2017Review
- Trimethyltin Modulates Reelin Expression and Endogenous Neurogenesis in the Hippocampus of Developing Rats.Neurochemical research · 2016Article
- CXCL12/CXCR4 Axis Improves Migration of Neuroblasts Along Corpus Callosum by Stimulating MMP-2 Secretion After Traumatic Brain Injury in Rats.Neurochemical research · 2016Article
- Proliferation and Glia-Directed Differentiation of Neural Stem Cells in the Subventricular Zone of the Lateral Ventricle and the Migratory Pathway to the Lesions after Cortical Devascularization of Adult Rats.BioMed research international · 2016Article
- Traumatic Brain Injury Activation of the Adult Subventricular Zone Neurogenic Niche.Frontiers in neuroscience · 2016Review
- The presence of stem cells in potential stem cell niches of the intervertebral disc region: an in vitro study on rats.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2015Article
- Review
- KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo.Cerebral cortex (New York, N.Y. : 1991) · 2014Article
- Influence of pigment epithelium-derived factor on outcome after striatal cerebral ischemia in the mouse.PloS one · 2014Article
- Article
- Cortical contusion injury disrupts olfactory bulb neurogenesis in adult mice.BMC neuroscience · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last few decades great thrust has been put in the area of regenerative neurobiology research to combat brain injuries and neurodegenerative diseases. The recent discovery of neurogenic niches in the adult brain has led researchers to study how to mobilize these cells to orchestrate an endogenous repair mechanism. The brain can minimize injury-induced damage by means of an immediate glial response and by initiating repair mechanisms that involve the generation and mobilization of new neurons to the site of injury where they can integrate into the existing circuit. This review highlights the current status of research in this field. Here, we discuss the changes that take place in the neurogenic milieu following injury. We will focus, in particular, on the cellular and molecular controls that lead to increased proliferation in the Sub ventricular Zone (SVZ) as well as neurogenesis. We will also concentrate on how these cellular and molecular mechanisms influence the migration of new cells to the affected area and their differentiation into neuronal/glial lineage that initiate the repair mechanism. Next, we will discuss some of the different factors that limit/retard the repair process and highlight future lines of research that can help to overcome these limitations. A clear understanding of the underlying molecular mechanisms and physiological changes following brain damage and the subsequent endogenous repair should help us develop better strategies to repair damaged brains.
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