ArticleMacromolecular bioscience2012
Development of channeled nanofibrous scaffolds for oriented tissue engineering.
Article in Macromolecular bioscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Properties of Resorbable Conduits Based on Poly(L-Lactide) Nanofibers and Chitosan Fibers for Peripheral Nerve Regeneration.Polymers · 2023Article
- Collagen for neural tissue engineering: Materials, strategies, and challenges.Materials today. Bio · 2023Review
- Biofabrication for neural tissue engineering applications.Materials today. Bio · 2020Review
- Nanofiber-Based Multi-Tubular Conduits with a Honeycomb Structure for Potential Application in Peripheral Nerve Repair.Macromolecular bioscience · 2018Article
- Poly(lactic acid) nanofibrous scaffolds for tissue engineering.Advanced drug delivery reviews · 2016Review
- Clinical Application of Mesenchymal Stem Cells and Novel Supportive Therapies for Oral Bone Regeneration.BioMed research international · 2015Review
- Fabrication and characterization of biomimetic multichanneled crosslinked-urethane-doped polyester tissue engineered nerve guides.Journal of biomedical materials research. Part A · 2014Article
- Fabrication and evaluation of PLLA multichannel conduits with nanofibrous microstructure for the differentiation of NSCs in vitro.Tissue engineering. Part A · 2014Article
- Article
- Nanofiber-based polyethersulfone scaffold and efficient differentiation of human induced pluripotent stem cells into osteoblastic lineage.Molecular biology reports · 2013Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
A tissue-engineering scaffold resembling the structure of the natural extracellular matrix can often facilitate tissue regeneration. Nerve and tendon are oriented micro-scale tissue bundles. In this study, a method combining injection molding and thermally induced phase separation techniques is developed to create single- and multiple-channeled nanofibrous poly(L-lactic acid) scaffolds. The overall shape, the number and spatial arrangement of channels, the channel wall matrix architecture, the porosity and mechanical properties of the scaffolds are all tunable. The porous NF channel wall matrix provides an excellent microenvironment for protein adsorption and the attachment of PC12 neuronal cells and tendon fibroblast cells, showing potential for neural and tendon tissue regeneration.
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Registered trials
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