Evidence map›Paper›PMID 22508462›Full record

ReviewNature reviews. Urology2012

New strategies to prevent catheter-associated urinary tract infections.

Danish M Siddiq, Rabih O Darouiche

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02277171 (Prospective, Phase I, Single-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters in Patients Undergoing Radical Prostatectomy), which is not on this map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02277171 phase1completednot on this mapstarted 2014, after this paper: background citation

Prospective, Phase I, Single-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters in Patients Undergoing Radical Prostatectomy

TypeinterventionalSponsorEnox Israel LtdRan2014 to 2015Enrolled15ConditionsUrinary Tract Infection, BacteriuriaArmsNitric Oxide impregnated catheter
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 166 citations in OpenAlex.

  1. Trial
  2. Article
  3. L-Fucose-Dependent Biofilm Formation bybioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Urinary tract infections and catheter-associated urinary tract infections caused byMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Using Lactobacilli to FightAntibiotics (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Danish M SiddiqDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, BCM 286, Room N-1319, 1 Baylor Plaza, Houston, TX 77030-3498, USA. siddiq@bcm.edu
Rabih O Darouiche
Baylor College of Medicine · USMichael E. DeBakey VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catheter-associated urinary tract infection (CAUTI) is the most common health-care-associated infection worldwide. Although not all cases of bacteriuria result in clinical infection, several hundred thousand episodes of CAUTI occur each year in the USA alone. The milieu in which the catheter is placed is highly conducive to bacterial colonization, biofilm formation on the catheter surface, and inevitable catheter-associated bacteriuria. A multitude of novel methods of CAUTI prevention have been described, including established approaches that are routinely recommended, such as the use of a secured, closed, silicone urinary catheter drainage system that mimics normal voiding, and newer strategies focusing on biocompatible catheter materials that cause minimal host inflammatory response and retard biofilm formation. Much recent research has focused on modification of the catheter surface by either coating or impregnation with antimicrobials or antiseptics. However, clinical trials that analyse cost-effectiveness and rates of antimicrobial resistance are awaited. More recently, innovative use of iontophoresis, vibroacoustic stimulation, bacterial interference and bacteriophage cocktails has been reported.

Indexed as

AnimalsAnti-Infective AgentsCatheters, IndwellingEquipment ContaminationEquipment DesignHumansUrinary CatheterizationUrinary Tract InfectionsAnti-Infective Agents

Identifiers

PMID22508462
OpenAlexW2094297275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.