Evidence map›Paper›PMID 22507743›Full record

ArticleInternational journal of epidemiology2013

Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children.

Andy Boyd, Jean Golding, John Macleod, Debbie A Lawlor, Abigail Fraser, John Henderson, Lynn Molloy, Andy Ness, Susan Ring, George Davey Smith

Abstract readHistorical Article
In one paragraph

Article in International journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,924 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,924citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,924 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  5. Assessing the causal effects of environmental tobacco smoke exposure: a meta-analytic Mendelian randomization study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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  14. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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1,864 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Andy BoydSchool of Social and Community Medicine, University of Bristol, Bristol, UK. a.w.boyd@bristol.ac.uk
Jean Golding
John Macleod
Debbie A Lawlor
Abigail Fraser
John Henderson
Lynn Molloy
Andy Ness
Susan Ring
George Davey Smith

Funding

Medical Research Council G0600705Medical Research Council G0701594Medical Research Council G9815508Wellcome Trust 092731Wellcome Trust 86118/Z/08/Z
6 · The paper itself

Abstract

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a transgenerational prospective observational study investigating influences on health and development across the life course. It considers multiple genetic, epigenetic, biological, psychological, social and other environmental exposures in relation to a similarly diverse range of health, social and developmental outcomes. Recruitment sought to enroll pregnant women in the Bristol area of the UK during 1990-92; this was extended to include additional children eligible using the original enrollment definition up to the age of 18 years. The children from 14541 pregnancies were recruited in 1990-92, increasing to 15247 pregnancies by the age of 18 years. This cohort profile describes the index children of these pregnancies. Follow-up includes 59 questionnaires (4 weeks-18 years of age) and 9 clinical assessment visits (7-17 years of age). The resource comprises a wide range of phenotypic and environmental measures in addition to biological samples, genetic (DNA on 11343 children, genome-wide data on 8365 children, complete genome sequencing on 2000 children) and epigenetic (methylation sampling on 1000 children) information and linkage to health and administrative records. Data access is described in this article and is currently set up as a supported access resource. To date, over 700 peer-reviewed articles have been published using ALSPAC data.

Indexed as

Child DevelopmentHealth StatusLongitudinal StudiesParentsAdolescentAnthropometryBlood BanksChildEnglandEnvironmentFemaleGenome-Wide Association StudyHealth BehaviorHistory, 20th CenturyHumansMale

Identifiers

PMID22507743
PMCPMC3600618

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.