Evidence map›Paper›PMID 22507742›Full record

ArticleInternational journal of epidemiology2013

Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort.

Abigail Fraser, Corrie Macdonald-Wallis, Kate Tilling, Andy Boyd, Jean Golding, George Davey Smith, John Henderson, John Macleod, Lynn Molloy, Andy Ness and 3 more

Abstract read
In one paragraph

Article in International journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,602 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,602citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,602 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  5. Assessing the causal effects of environmental tobacco smoke exposure: a meta-analytic Mendelian randomization study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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1,542 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Abigail FraserMRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK.
Corrie Macdonald-Wallis
Kate Tilling
Andy Boyd
Jean Golding
George Davey Smith
John Henderson
John Macleod
Lynn Molloy
Andy Ness
Susan Ring
Scott M Nelson
Debbie A Lawlor

Funding

Maternal overnutrition and offspring fat mass, metabolic and vascular function.R01DK077659 · NIDDK · UNIVERSITY OF BRISTOL · PI LAWLOR, DEBORAH ANNE · 2006 to 2009
$986k
British Heart Foundation SP/07 1008/24066Medical Research Council G0600705Medical Research Council G0701594Medical Research Council G1001357Medical Research Council G9815508NIDDK NIH HHS R01 DK077659Wellcome Trust 087997MAWellcome Trust 088806Wellcome Trust 092731Wellcome Trust 92830/Z/10/Z
6 · The paper itself

Abstract

Summary The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children. All pregnant women resident in a defined area in the South West of England, with an expected date of delivery between 1st April 1991 and 31st December 1992, were eligible and 13761 women (contributing 13867 pregnancies) were recruited. These women have been followed over the last 19-22 years and have completed up to 20 questionnaires, have had detailed data abstracted from their medical records and have information on any cancer diagnoses and deaths through record linkage. A follow-up assessment was completed 17-18 years postnatal at which anthropometry, blood pressure, fat, lean and bone mass and carotid intima media thickness were assessed, and a fasting blood sample taken. The second follow-up clinic, which additionally measures cognitive function, physical capability, physical activity (with accelerometer) and wrist bone architecture, is underway and two further assessments with similar measurements will take place over the next 5 years. There is a detailed biobank that includes DNA, with genome-wide data available on >10000, stored serum and plasma taken repeatedly since pregnancy and other samples; a wide range of data on completed biospecimen assays are available. Details of how to access these data are provided in this cohort profile.

Indexed as

Health StatusLongitudinal StudiesMothersAdultAnthropometryBlood BanksBody Mass IndexChildDNA MethylationEnglandFemaleGenome-Wide Association StudyHealth BehaviorHumansMedical Record LinkageParents

Identifiers

PMID22507742
PMCPMC3600619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.