ReviewPeriodontology 20002012
Advanced reconstructive technologies for periodontal tissue repair.
Review in Periodontology 2000, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Appraising and comparing the role of autogenous periosteal graft as a barrier membrane in the treatment of intrabony defects in chronic periodontitis cases: A systematic review and meta-analysis.International journal of medical sciences · 2024Pooled it
- A novel flapless approach versus minimally invasive surgery in periodontal regeneration with enamel matrix derivative proteins: a 24-month randomized controlled clinical trial.Clinical oral investigations · 2017Trial
- Platelet-derived growth factor promotes periodontal regeneration in localized osseous defects: 36-month extension results from a randomized, controlled, double-masked clinical trial.Journal of periodontology · 2013Trial
- Comparative evaluation of open flap debridement with or without injectable platelet-rich fibrin in chronic periodontitis treatment.Bioinformation · 2026Article
- Evaluation of the Clinical Efficacy of Copine 7-Derived Peptides for Naturally Occurring Periodontitis in Dogs.Journal of clinical periodontology · 2025Article
- Beneficial Effect of Platelet-Rich Fibrin as an Adjunct to Nonsurgical Therapy After Subgingival Professional Mechanical Plaque Removal for Periodontitis: A Systematic Review and Meta-Analysis.Clinics and practice · 2025Review
- Article
- Potential of Trilayered Gelatin/Polycaprolactone Nanofibers for Periodontal Regeneration: An In Vitro Study.International journal of molecular sciences · 2025Article
- Hierarchical Biomaterial Scaffolds for Periodontal Tissue Engineering: Recent Progress and Current Challenges.International journal of molecular sciences · 2024Review
- From Basic Science to Clinical Practice: A Review of Current Periodontal/Mucogingival Regenerative Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Management of a severely atrophic maxilla using concentrated platelet-rich fibrin block. A case report.Journal of surgical case reports · 2024Article
- The construction of a microenvironment with the vascular network by co-culturing fibroblasts and endothelial cells.Regenerative therapy · 2024Article
- Bioactive injectable mucoadhesive thermosensitive natural polymeric hydrogels for oral bone and periodontal regeneration.Frontiers in bioengineering and biotechnology · 2024Review
- New Insights in Hydrogels for Periodontal Regeneration.Journal of functional biomaterials · 2023Review
- Enamel Matrix Derivative (EMD) as an Adjunct to Non-surgical Periodontal Therapy: A Systematic Review.Cureus · 2023Review
- 3D-Printed Soft Membrane for Periodontal Guided Tissue Regeneration.Materials (Basel, Switzerland) · 2023Article
- Macro, Micro, and Nano-Inspired Bioactive Polymeric Biomaterials in Therapeutic, and Regenerative Orofacial Applications.Drug design, development and therapy · 2023Review
- The role of extracellular vesicles in periodontitis: pathogenesis, diagnosis, and therapy.Frontiers in immunology · 2023Review
- Collagen Membrane Derived from Fish Scales for Application in Bone Tissue Engineering.Polymers · 2022Article
- Investigating the Effects of Dehydrated Human Amnion-Chorion Membrane on Periodontal Healing.Biomolecules · 2022Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Reconstructive therapies to promote the regeneration of lost periodontal support have been investigated through both preclinical and clinical studies. Advanced regenerative technologies using new barrier-membrane techniques, cell-growth-stimulating proteins or gene-delivery applications have entered the clinical arena. Wound-healing approaches using growth factors to target the restoration of tooth-supporting bone, periodontal ligament and cementum are shown to significantly advance the field of periodontal-regenerative medicine. Topical delivery of growth factors, such as platelet-derived growth factor, fibroblast growth factor or bone morphogenetic proteins, to periodontal wounds has demonstrated promising results. Future directions in the delivery of growth factors or other signaling models involve the development of innovative scaffolding matrices, cell therapy and gene transfer, and these issues are discussed in this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.