ArticleAnnals of rehabilitation medicine2012
The correlation analysis of functional factors and age with duchenne muscular dystrophy.
Article in Annals of rehabilitation medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Article
- A 5-year natural history study in LAMA2-related muscular dystrophy and SELENON-related myopathy: the Extended LAST STRONG study.BMC neurology · 2024Observational
- Validity of the Functional Classification of the Upper Extremities for Duchenne Muscular Dystrophy.Progress in rehabilitation medicine · 2024Article
- The efficacy of different torque profiles for weight compensation of the hand.Wearable technologies · 2024Article
- Real-time myoelectric control of wrist/hand motion in Duchenne muscular dystrophy: A case study.Frontiers in robotics and AI · 2023Article
- Quality of life and informal care burden associated with duchenne muscular dystrophy in Portugal: the COIDUCH study.Health and quality of life outcomes · 2022Article
- Cost of Illness in Patients with Duchenne Muscular Dystrophy in Portugal: The COIDUCH Study.PharmacoEconomics - open · 2022Article
- A Machine-Learning Method of Predicting Vital Capacity Plateau Value for Ventilatory Pump Failure Based on Data Mining.Healthcare (Basel, Switzerland) · 2021Article
- Serum creatinine as a biomarker for dystrophinopathy: a cross-sectional and longitudinal study.BMC neurology · 2021Article
- Natural history, outcome measures and trial readiness in LAMA2-related muscular dystrophy and SELENON-related myopathy in children and adults: protocol of the LAST STRONG study.BMC neurology · 2021Article
- Autonomic Modulation in Duchenne Muscular Dystrophy During a Computer Task: A Prospective Transversal Controlled Trial Assessment by Non-linear Techniques.Frontiers in neurology · 2021Article
- Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy.Journal of neurology · 2020Article
- Analysis of Different Device Interactions in a Virtual Reality Task in Individuals With Duchenne Muscular Dystrophy-A Randomized Controlled Trial.Frontiers in neurology · 2019Article
- A New Functional Scale and Ambulatory Functional Classification of Duchenne Muscular Dystrophy: Scale Development and Preliminary Analyses of Reliability and Validity.Annals of rehabilitation medicine · 2018Article
- HLA Polymorphism Affects Risk ofFrontiers in neurology · 2018Article
- Autonomic Modulation in Duchenne Muscular Dystrophy during a Computer Task: A Prospective Control Trial.PloS one · 2017Article
- Serum creatinine level: a supplemental index to distinguish Duchenne muscular dystrophy from Becker muscular dystrophy.Disease markers · 2015Article
- Patterns of decline in upper limb function of boys and men with DMD: an international survey.Journal of neurology · 2014Article
- Design requirements of upper extremity supports for daily use in Duchenne muscular dystrophy with severe muscle weakness.Journal of rehabilitation and assistive technologies engineeringArticle
- Relationship between the climbing up and climbing down stairs domain scores on the FES-DMD, the score on the Vignos Scale, age and timed performance of functional activities in boys with Duchenne muscular dystrophy.Brazilian journal of physical therapyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo correlate existing evaluation tools with clinical information on Duchenne muscular dystrophy (DMD) patients following age and to investigate genetic mutation and its relationship with clinical function.
methodThe medical records of 121 children with DMD who had visited the pediatric rehabilitation clinic from 2006 to 2009 were reviewed. The mean patient age was 9.9±3.4 years and all subjects were male. Collected data included Brooke scale, Vignos scale, bilateral shoulder abductor and knee extensor muscles power, passive range of motion (PROM) of ankle dorsi-flexion, angle of scoliosis, peak cough flow (PCF), fractional shortening (FS), genetic abnormalities, and use of steroid.
resultsThe Brooke and Vignos scales were linearly increased with age (Brooke (y(1)), Vignos (y(2)), age (x), y(1)=0.345x-1.221, R(Brooke) (2)=0.435, y(2)=0.813x-3.079, R(Vignos) (2)=0.558, p<0.001). In relation to the PROM of ankle dorsi-flexion, there was a linear decrease in both ankles (right and left R(2)=0.364, 0.372, p<0.001). Muscle power, Cobb angle, PCF, and FS showed diversity in their degrees, irrespective of age. The genetic test for dystrophin identified exon deletions in 58.0% (69/119), duplications in 9.2% (11/119), and no deletions or duplications in 32.8% (39/119). Statistically, the genetic abnormalities and use of steroid were not definitely associated with functional scale.
conclusionThe Brooke scale, Vignos scale and PROM of ankle dorsi-flexion were partially available to assess DMD patients. However, this study demonstrates the limitations of preexisting scales and clinical parameters incomprehensively reflecting functional changes of DMD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.