SynthesisJournal of environmental and public health2012
Arsenic, cadmium, lead, and mercury in sweat: a systematic review.
Synthesis in Journal of environmental and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 104 citations in OpenAlex.
- In-Series Production of Integrated Bi-Doped Laser-Induced Graphene Sensors for Simultaneous Detection of Zn(II), Cd(II), and Pb(II).ACS measurement science au · 2026Article
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Sweat as a diagnostic biofluid: analytical advances and future directions.Journal of pharmaceutical analysis · 2026Review
- Multi-Targeted Mechanisms of Phytochemicals in Mitigating Cadmium-Induced Breast Cancer.Medicines (Basel, Switzerland) · 2026Review
- Chronic Lead Exposure and Tauopathies: Molecular Mechanisms of Neurotoxicity and Emerging Nanotherapeutic Strategies.Journal of toxicology · 2026Review
- Mapping Multi-Modal Fatigue in Elite Soccer Through Sweat-Omics Perspectives: A Narrative Review.Biology · 2025Review
- Differential impacts of physical activity volume and intensity on blood lead levels in children and adolescents: a cross-sectional study.BMC public health · 2025Article
- The Effect of Physical Activity on Combined Cadmium, Lead, and Mercury Exposure.Medical sciences (Basel, Switzerland) · 2024Article
- Magnetic Porous Hydrogel-Enhanced Wearable Patch Sensor for Sweat Zinc Ion Monitoring.Sensors (Basel, Switzerland) · 2024Article
- Biochar as Alternative Material for Heavy Metal Adsorption from Groundwaters: Lab-Scale (Column) Experiment Review.Materials (Basel, Switzerland) · 2024Review
- Addressing the Missing Links in Cardiovascular Aging.Clinical interventions in aging · 2024Review
- Clinical applications of smart wearable sensors.iScience · 2023Review
- A State-of-the-Science Review on Metal Biomarkers.Current environmental health reports · 2023Review
- Interaction between blood cadmium and lead concentration and physical activity on hypertension from the Korean national health and nutrition examination survey in 2008-2013.BMC public health · 2023Article
- A Review of Skin-Wearable Sensors for Non-Invasive Health Monitoring Applications.Sensors (Basel, Switzerland) · 2023Review
- Assessment of heavy metals among auto workers in metropolitan city: a case study.Frontiers in public health · 2023Article
- Wearable and flexible electrochemical sensors for sweat analysis: a review.Microsystems & nanoengineering · 2023Review
- The Coming of Age of AI/ML in Drug Discovery, Development, Clinical Testing, and Manufacturing: The FDA Perspectives.Drug design, development and therapy · 2023Article
- Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem.Phenomics (Cham, Switzerland) · 2022Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Arsenic, cadmium, lead, and mercury exposures are ubiquitous. These toxic elements have no physiological benefits, engendering interest in minimizing body burden. The physiological process of sweating has long been regarded as "cleansing" and of low risk. Reports of toxicant levels in sweat were sought in Medline, Embase, Toxline, Biosis, and AMED as well as reference lists and grey literature, from inception to March 22, 2011. Of 122 records identified, 24 were included in evidence synthesis. Populations, and sweat collection methods and concentrations varied widely. In individuals with higher exposure or body burden, sweat generally exceeded plasma or urine concentrations, and dermal could match or surpass urinary daily excretion. Arsenic dermal excretion was severalfold higher in arsenic-exposed individuals than in unexposed controls. Cadmium was more concentrated in sweat than in blood plasma. Sweat lead was associated with high-molecular-weight molecules, and in an interventional study, levels were higher with endurance compared with intensive exercise. Mercury levels normalized with repeated saunas in a case report. Sweating deserves consideration for toxic element detoxification. Research including appropriately sized trials is needed to establish safe, effective therapeutic protocols.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.