ArticleInternational journal of endocrinology2012
Role of surrogate markers of atherosclerosis in clinical and subclinical thyroidism.
Article in International journal of endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of methylenetetrahydrofolate reductase (Archives of endocrinology and metabolismPooled it
- Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects.BioMed research international · 2015Trial
- The Relationship between Subclinical Hypothyroidism and Carotid Intima-Media Thickness as a Potential Marker of Cardiovascular Risk: A Systematic Review and a Meta-Analysis.Journal of cardiovascular development and disease · 2024Review
- Dyslipidaemia and inflammatory markers as the risk predictors for cardiovascular disease in newly diagnosed premenopausal hypothyroid women.Journal of medical biochemistry · 2023Article
- The Effect of Early Substitution of Subclinical Hypothyroidism on Biochemical Blood Parameters and the Quality of Life.Journal of medical biochemistry · 2017Article
- MMP-9 Levels and IMT of Carotid Arteries are Elevated in Obese Children and Adolescents Compared to Non-Obese.Arquivos brasileiros de cardiologia · 2017Article
- Homocysteine diminishes apolipoprotein A-I function and expression in patients with hypothyroidism: a cross-sectional study.Lipids in health and disease · 2016Article
- Potential harmful correlation between homocysteine and low-density lipoprotein cholesterol in patients with hypothyroidism.Medicine · 2016Article
- Protective Role of Bilirubin Against Increase in hsCRP in Different Stages of Hypothyroidism.Indian journal of clinical biochemistry : IJCB · 2016Article
- Serum H-FABP levels in patients with hypothyroidism.Wiener klinische Wochenschrift · 2014Article
- Evaluation of epicardial fat tissue thickness in patients with hyperthyroidism.Wiener klinische Wochenschrift · 2014Article
- Serum homocysteine levels are decreased in levothyroxine-treated women with autoimmune thyroiditis.BMC endocrine disorders · 2014Article
- Relationship between total homocysteine, total cholesterol and creatinine levels in overt hypothyroid patients.SpringerPlus · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Data on the relationship between homocysteine, plasminogen activator inhibitor 1, hs-CRP, fibrinogen, and carotid intima media thickness (CA-IMT) is plenty but contradicting and the majority of the studies investigated this issue in only specific thyroidism groups. The aim of this paper was to investigate these relations in patients with subclinical and clinical hypo- and hyperthyroidism. Methods. In this cross-sectional study, 16 patients from each thyroidism group and 20 healthy cases were enrolled. Fibrinogen levels and plasminogen activator inhibitor 1 (PAI-1) activity were assessed. CA-IMT was determined by gray-scale high-resolution color Doppler ultrasound. Results. Serum homocysteine levels were higher in hypothyroidic patients compared to the control (P = 0.003). Fibrinogen levels were higher in patients with subclinical hypothyroidism compared to other groups (P < 0.05). There was no difference between groups regarding PAI-1. Whereas total cholesterol, homocysteine, and LDL were correlated with CAIMT, hs-CRP, PAI-1, and fibrinogen were not. In the clinical hypothyroidism group, the correlation of homocysteine with CA-IMT was derived from the correlation between CA-IMT and homocysteine. Conclusions. Homocysteine and fibrinogen levels are higher in patients with clinical and subclinical hypothyroidism, respectively. Homocysteine level is associated with CA-IMTonly in patients with clinical hypothyroidism.
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