Evidence map›Paper›PMID 22505813›Full record

ReviewJournal of biomedicine & biotechnology2012

PET/CT imaging in mouse models of myocardial ischemia.

Sara Gargiulo, Adelaide Greco, Matteo Gramanzini, Maria Piera Petretta, Adele Ferro, Michele Larobina, Mariarosaria Panico, Arturo Brunetti, Alberto Cuocolo

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Multifunctional bioelectronics for brain-body circuits.Nature reviews bioengineering · 2025
    Article
  3. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. The long way to defeating Chagas cardiomyopathy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Contrast media & molecular imaging · 2017
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sara GargiuloDepartment of Biomorphological and Functional Sciences and Institute of Biostructures and Bioimages of National Council of Research, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy. sara.gargiulo@ibb.cnr.it
Adelaide Greco
Matteo Gramanzini
Maria Piera Petretta
Adele Ferro
Michele Larobina
Mariarosaria Panico
Arturo Brunetti
Alberto Cuocolo
University of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITInstitute of Biostructure and Bioimaging · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different species have been used to reproduce myocardial infarction models but in the last years mice became the animals of choice for the analysis of several diseases, due to their short life cycle and the possibility of genetic manipulation. Many techniques are currently used for cardiovascular imaging in mice, including X-ray computed tomography (CT), high-resolution ultrasound, magnetic resonance imaging, and nuclear medicine procedures. Cardiac positron emission tomography (PET) allows to examine noninvasively, on a molecular level and with high sensitivity, regional changes in myocardial perfusion, metabolism, apoptosis, inflammation, and gene expression or to measure changes in anatomical and functional parameters in heart diseases. Currently hybrid PET/CT scanners for small laboratory animals are available, where CT adds high-resolution anatomical information. This paper reviews mouse models of myocardial infarction and discusses the applications of dedicated PET/CT systems technology, including animal preparation, anesthesia, radiotracers, and images postprocessing.

Indexed as

Disease Models, AnimalPositron-Emission TomographyTomography, X-Ray ComputedAnimalsMiceMultimodal ImagingMyocardial Ischemia

Identifiers

PMID22505813
PMCPMC3312322
OpenAlexW2127438736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.