Evidence map›Paper›PMID 22505475›Full record

ArticleJournal of the National Cancer Institute2012

Molecular scores to predict ovarian cancer outcomes: a worthy goal, but not ready for prime time.

Elizabeth M Swisher, Toshiyasu Taniguchi, Beth Y Karlan

Abstract readEditorialComment
In one paragraph

Article in Journal of the National Cancer Institute, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Single-sample expression-based chemo-sensitivity score improves survival associations independently from genomic mutations for ovarian cancer Patients.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Elizabeth M Swisher
Toshiyasu Taniguchi
Beth Y Karlan

Funding

Vaccinating against IGFBP-2 to prevent ovarian cancer relapseP50CA083636 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DRESCHER, CHARLES, URBAN, NICOLE DENISE · 1999 to 2015
$35.1M
The Fanconi Anemia-BRCA Pathway And Chemosensitivity of Human CancerR01CA125636 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TANIGUCHI, TOSHIYASU · 2007 to 2011
$1.6M
Defining a Pre-Malignant Phenotype in Fallopian Tube EpitheliumR01CA131965 · NCI · UNIVERSITY OF WASHINGTON · PI SWISHER, ELIZABETH MARY · 2009 to 2013
$1.6M
Howard Hughes Medical InstituteNCI NIH HHS P50 CA083636NCI NIH HHS P50CA83636NCI NIH HHS R01 CA125636NCI NIH HHS R01CA125636NCI NIH HHS R01CA131965
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorDNA RepairFemaleHumansOvarian NeoplasmsBiomarkers, Tumor

Identifiers

PMID22505475
PMCPMC3341312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.