ReviewNature neuroscience2012
The animal and human neuroendocrinology of social cognition, motivation and behavior.
Review in Nature neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
116 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of psychosocial functioning changes after gender-affirming hormone therapy among transgender people.Nature human behaviour · 2023Pooled it
- The effect of intranasal oxytocin on neural response to facial emotions in healthy adults as measured by functional MRI: A systematic review.Psychiatry research. Neuroimaging · 2018Pooled it
- Neurophysiological effects of acute oxytocin administration: systematic review and meta-analysis of placebo-controlled imaging studies.Journal of psychiatry & neuroscience : JPN · 2015Pooled it
- Reducing neuroendocrine psychosocial stress response through socio-emotional dyadic but not mindfulness online training.Frontiers in endocrinology · 2024Trial
- Sex differences in the effects of aromatherapy on anxiety and salivary oxytocin levels.Frontiers in endocrinology · 2024Trial
- Does testosterone impair men's cognitive empathy? Evidence from two large-scale randomized controlled trials.Proceedings. Biological sciences · 2019Trial
- Trial
- Oxytocin modulates social distance between males and females.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Trial
- Trial
- Oxytocin Variants Induce Cellular Signaling and Neurite Outgrowth in Human-Derived Neuron-like SH-SY5Y Cell Line.NeuroSci · 2026Article
- Testosterone, cortisol, and fNIRS-based cortical activation associated with competitive task persistence and difficulty.Journal of neuroendocrinology · 2026Article
- Interoceptive Information of Physical Vigor Through Circulating Insulin-Like Growth Factor 1.FASEB bioAdvances · 2026Article
- Examination of positive states of mind and heart rate variability: Stress appraisals as a mechanism in trauma-exposed adults.Psychoneuroendocrinology · 2025Article
- Oxytocin and opioid antagonists: A dual approach to improving social behavior.Annals of the New York Academy of Sciences · 2025Review
- Effects of low concentration of fluoride exposure during fetal on behavior and neurotransmitters in adult mice.Biomedical reports · 2025Article
- A multidimensional approach to the self in non-human animals through the Pattern Theory of Self.Frontiers in psychology · 2025Article
- Resilience phenotypes derived from an active inference account of allostasis.Frontiers in behavioral neuroscience · 2025Article
- Article
- Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice.Frontiers in endocrinology · 2024Article
- The Optimal Time-lag for Testosterone Challenge Research Based on Salivary Profiles Following Different Doses of Transdermal Testosterone Administrations.Journal of molecular neuroscience : MN · 2023Article
56 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive animal and recent human research have helped inform neuroendocrinological models of social cognition, motivation and behavior. In this review, we first summarize important findings regarding oxytocin, arginine vasopressin and testosterone in the domains of affiliation, social cognition, aggression and stress/anxiety. We then suggest ways in which human research can continue to profit from animal research, particularly by exploring the interactive nature of neuromodulatory effects at neurochemical, organismic and contextual levels. We further propose methods inspired by the animal literature for the ecologically valid assessment of affiliative behavior in humans. We conclude with suggestions for how human research could advance by directly assessing specific social cognitive and motivational mechanisms as intermediate variables. We advocate a more comprehensive look at the distinct networks identified by social neuroscience and the importance of a motivational state, in addition to approach and avoidance, associated with quiescence and homeostatic regulation.
Indexed as
Identifiers
22504348What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.