ArticleGeneral and comparative endocrinology2012
Conservation of the photoperiodic neuroendocrine axis among vertebrates: evidence from the teleost fish, Gasterosteus aculeatus.
Article in General and comparative endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 34 citations in OpenAlex.
- Dim light at night induces cardiac injury in zebrafish embryos via disrupted chloride homeostasis.iScience · 2026Article
- Interaction Between Photoperiod and Gonadal Feedback onZoological studies · 2026Article
- Functional mutations in the thyroid-stimulating hormone receptor in natural stickleback populations at sites identical to human disease-causing mutations.BMC ecology and evolution · 2025Article
- Misbalance of thyroid hormones after two weeks of exposure to artificial light at night in Eurasian perchConservation physiology · 2021Article
- Prior exposure to long-day photoperiods alters immune responses and increases susceptibility to parasitic infection in stickleback.Proceedings. Biological sciences · 2020Article
- Physical Cues Controlling Seasonal Immune Allocation in a Natural Piscine Model.Frontiers in immunology · 2018Article
- Disrupted seasonal biology impacts health, food security and ecosystems.Proceedings. Biological sciences · 2015Review
- Changes in vasotocin levels in relation to ovarian development in the catfish Heteropneustes fossilis exposed to altered photoperiod and temperature.Fish physiology and biochemistry · 2015Article
- Perchlorate exposure does not modulate temporal variation of whole-body thyroid and androgen hormone content in threespine stickleback.General and comparative endocrinology · 2015Article
- Thyroid hormone and seasonal rhythmicity.Frontiers in endocrinology · 2014Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Photoperiod, or length of day, has a predictable annual cycle, making it an important cue for the timing of seasonal behavior and development in many organisms. Photoperiod is widely used among temperate and polar animals to regulate the timing of sexual maturation. The proper sensing and interpretation of photoperiod can be tightly tied to an organism's overall fitness. In photoperiodic mammals and birds the thyroid hormone pathway initiates sexual maturation, but the degree to which this pathway is conserved across other vertebrates is not well known. We use the threespine stickleback Gasterosteus aculeatus, as a representative teleost to quantify the photoperiodic response of key genes in the thyroid hormone pathway under controlled laboratory conditions. We find that the photoperiodic responses of the hormones are largely consistent amongst multiple populations, although differences suggest physiological adaptation to various climates. We conclude that the thyroid hormone pathway initiates sexual maturation in response to photoperiod in G. aculeatus, and our results show that more components of this pathway are conserved among mammals, birds, and teleost fish than was previously known. However, additional endocrinology, cell biology and molecular research will be required to define precisely which aspects of the pathway are conserved across vertebrates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.