Evidence map›Paper›PMID 22502720›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2012

HPV prevalence and cervical intraepithelial neoplasia among HIV-infected women in Yunnan Province, China: a pilot study.

Hong-Yun Zhang, Sarah M Tiggelaar, Vikrant V Sahasrabuddhe, Jennifer S Smith, Cheng-Qin Jiang, Run-Bo Mei, Xian-Guo Wang, Zu-An Li, You-Lin Qiao

Open access · goldAbstract readComparative Study
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

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  5. Review
  6. Article
  7. Human Papillomavirus (HPV) Prevalence and Type Distribution in Urban Areas of Malaysia.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  8. Cervical Cancer Screening in HIV-Positive Women in India: Why, When and How?Journal of obstetrics and gynaecology of India · 2021
    Article
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  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Hong-Yun ZhangKunming Medical University, Kunming, China.
Sarah M Tiggelaar
Vikrant V Sahasrabuddhe
Jennifer S Smith
Cheng-Qin Jiang
Run-Bo Mei
Xian-Guo Wang
Zu-An Li
You-Lin Qiao
Boston Children's Hospital · USAcademy of Medical Sciences · GBKunming Medical University · CNVanderbilt University · US

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
Vanderbilt University-CIDRZ AIDS International Training and Research ProgramD43TW001035 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 1998 to 2014
$10.9M
VIROLOGY COREP30AI054999 · NIAID · VANDERBILT UNIVERSITY · PI D'AQUILA, RICHARD · 2003 to 2011
$10.3M
Vanderbilt-Meharry Framework Program for Global HealthR25TW007766 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2006 to 2008
$371k
FIC NIH HHS D43 TW001035FIC NIH HHS D43TW001035FIC NIH HHS R24 TW007988FIC NIH HHS R24TW007988FIC NIH HHS R25 TW007766NIAID NIH HHS P30 AI054999NIAID NIH HHS P30AI054999
6 · The paper itself

Abstract

objectivesTo determine the prevalence of HPV and cervical neoplasia among HIV-infected women in southwestern China.

methodsCervical cytology, HPV detection by Hybrid Capture-2™ assay, and diagnostic colposcopy were followed by cervical biopsy if indicated. Logistic regression analysis was used to analyze associations between HPV co-infection and cervical intraepithelial neoplasia (CIN), and HIV-related clinical and laboratory parameters.

resultsColposcopic-histopathologically proven CIN2+ lesions were present in 7/83 (8.4%) HIV-infected women. Nearly half (41/83, 43%) were co-infected with carcinogenic HPV genotypes. HPV co-infection was higher in women with colposcopic-histopathologically proven CIN2+ lesions than women with <CIN1 after adjusting for age (OR: 8.3, 95% CI: 0.9, 73.4). Women with CD4+ cell counts less than 350 cells/μL had higher CIN2+ prevalence after adjusting for current ART status and age (adjusted OR: 6.3, 95% CI: 1.1, 36.5).

conclusionsHIV/AIDS care and treatment programs should integrate effective cervical cancer prevention services to mitigate the risk of invasive cervical cancer among HIV-infected women in China.

Indexed as

AdultAgedChinaCoinfectionColposcopyDNA, ViralFemaleHIVHIV InfectionsHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPilot ProjectsPolymerase Chain ReactionPrevalenceDNA, Viral

Identifiers

PMID22502720
PMCPMC3809115
OpenAlexW2118114259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.