ReviewJournal of natural products2012
Fungal origins of the bicyclo[2.2.2]diazaoctane ring system of prenylated indole alkaloids.
Review in Journal of natural products, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Sustainable Biocatalytic Cascades: A Versatile Tool in the Synthesis of Natural Products With Therapeutic Potential.Chembiochem : a European journal of chemical biology · 2026Review
- Total Synthesis of (+)-Malbrancheamide B Employing a Bioinspired Strategy.Organic letters · 2026Article
- Exploring the efficacy of new potential bio-insecticides produced by Penicillium oxalicum against Culex pipiens larvae.BMC microbiology · 2026Article
- Engineering a Biosynthetic Pathway to Produce (+)-Brevianamides A and B.ACS catalysis · 2025Article
- The Mutually Inspiring Biological and Chemical Synthesis of Fungal Bicyclo[2.2.2]diazaoctane Indole Alkaloids.Chemical reviews · 2025Review
- Sustainable Synthesis of Medicinally Important Heterocycles.Mini reviews in medicinal chemistry · 2025Review
- Aspertaichamide B, a new anti-tumor prenylated indole alkaloid from the fungus Aspergillus japonicus TE-739D.Applied microbiology and biotechnology · 2024Article
- Phytochemical analysis and anti-infective potential of fungal endophytes isolated from Nigella sativa seeds.BMC microbiology · 2023Article
- Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads.Marine drugs · 2022Article
- Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions.Marine drugs · 2022Review
- New Trends and Future Opportunities in the Enzymatic Formation of C-C, C-N, and C-O bonds.Chembiochem : a European journal of chemical biology · 2022Review
- Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1-Nrf2.Marine drugs · 2022Article
- Unified total synthesis of the brevianamide alkaloids enabled by chemical investigations into their biosynthesis.Chemical science · 2022Article
- A general approach to 2,2-disubstituted indoxyls: total synthesis of brevianamide A and trigonoliimine C.Chemical science · 2021Article
- Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides.Chembiochem : a European journal of chemical biology · 2020Article
- Natural Products from Endophytic Fungi Associated with Rubiaceae Species.Journal of fungi (Basel, Switzerland) · 2020Review
- Total synthesis of brevianamide A.Nature chemistry · 2020Article
- Fungal-derived brevianamide assembly by a stereoselective semipinacolase.Nature catalysis · 2020Article
- Synthesis of α-indolylacrylates as potential anticancer agents using a Brønsted acid ionic liquid catalyst and the butyl acetate solvent.RSC advances · 2020Article
- Convergent biosynthetic transformations to a bacterial specialized metabolite.Nature chemical biology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Over eight different families of natural products consisting of nearly 70 secondary metabolites that contain the bicyclo[2.2.2]diazaoctane ring system have been isolated from various Aspergillus, Penicillium, and Malbranchea species. Since 1968, these secondary metabolites have been the focus of numerous biogenetic, synthetic, taxonomic, and biological studies and, as such, have made a lasting impact across multiple scientific disciplines. This review covers the isolation, biosynthesis, and biological activity of these unique secondary metabolites containing the bridging bicyclo[2.2.2]diazaoctane ring system. Furthermore, the diverse fungal origin of these natural products is closely examined and, in many cases, updated to reflect the currently accepted fungal taxonomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.