Evidence map›Paper›PMID 22500191›Full record

ArticleF1000 medicine reports2012

Helicobacter pylori: Eradication or Preservation.

George Sachs, David R Scott

Abstract read
In one paragraph

Article in F1000 medicine reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Role of TRPV4 in the Diagnosis and Treatment ofBioMed research international · 2022
    Trial
  4. Validation of a Gastric-Juice-Analysis-Based Approach toDiagnostics (Basel, Switzerland) · 2026
    Article
  5. Co-Occurrence ofBiomedicines · 2025
    Review
  6. Association betweenBMJ open gastroenterology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Chilean Rhubarb,Frontiers in pharmacology · 2020
    Article
  13. Helicobacter pylori infection in children: an overview of diagnostic methods.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
  14. Review
  15. MUC1 and MUC5AC Acting onEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  16. Article
  17. Review
  18. [Kyoto global consensus report for treatment of Helicobacter pylori and its implications for China].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2016
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

George SachsMembrane Biology Laboratory, VA Greater Los Angeles Healthcare System West LA Medical Center, 11301 Wilshire Boulevard, Building 113, Room 324, Los Angeles, CA 90073 USA David Geffen School of Medicine, UCLA.
David R Scott

Funding

The Gastric Biology of Helicobacter PyloriR01DK053642 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SACHS, GEORGE · 1997 to 2012
$3.2M
THE GASTRIC ACID PUMP AS A TARGET FOR ULCER TREATMENTR01DK058333 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SACHS, GEORGE · 2000 to 2009
$2.6M
NIDDK NIH HHS R01 DK053642NIDDK NIH HHS R01 DK058333
6 · The paper itself

Abstract

Helicobacter pylori infects about 50% of the world's population and inevitably results in the development of gastritis. Of those infected, about 10% develop peptic ulcer disease and roughly 1% develop gastric cancer. Conversely, some take the view that H. pylori infection provides some protection against gastro-esophageal reflux disease and possibly asthma. This review aims to explore the case for and against eradication of the bacterium using a "test and treat" approach amongst the general population.

Identifiers

PMID22500191
PMCPMC3318258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.