ArticleAJNR. American journal of neuroradiology2012
Hemodynamic changes in patients with arteriovenous malformations assessed using high-resolution 3D radial phase-contrast MR angiography.
Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Diagnostic Performance of TOF, 4D MRA, Arterial Spin-Labeling, and Susceptibility-Weighted Angiography Sequences in the Post-Radiosurgery Monitoring of Brain AVMs.AJNR. American journal of neuroradiology · 2025Pooled it
- Optimal 4DFlow MR sequence parameters for the assessment of internal carotid artery stenosis: a simulation study.Neuroradiology · 2019Trial
- Intracranial 4D flow MRI: toward individualized assessment of arteriovenous malformation hemodynamics and treatment-induced changes.AJNR. American journal of neuroradiology · 2013Trial
- Arteriovenous Malformations (AVMs): Molecular Pathogenesis, Clinical Features, and Emerging Therapeutic Strategies.Biomolecules · 2025Review
- The Role of Angiographic Imaging in the Treatment of Spinal Vascular Malformations.Medical sciences (Basel, Switzerland) · 2025Review
- Simultaneous Multiparametric Estimation of AVM Hemodynamics Using MR Fingerprinting Arterial Spin-Labeling.AJNR. American journal of neuroradiology · 2025Article
- Feasibility Study for Multimodal Image-Based Assessment of Patient-Specific Intracranial Arteriovenous Malformation Hemodynamics.Journal of clinical medicine · 2025Article
- Comparison of silent MRA and time-of-flight MRA in the depiction and grading of brain arteriovenous malformations.Quantitative imaging in medicine and surgery · 2024Article
- Hemodynamic relationship with angioarchitecture of cerebral arteriovenous malformation and changes after embolization: a pilot study by 4D flow MR.Quantitative imaging in medicine and surgery · 2024Article
- Hemodynamic evaluation of intracranial arteriovenous malformations: Pre- and post-treatment 2D phase-contrast MRI measurements.Acta radiologica open · 2024Article
- Brain arteriovenous malformation flow after stereotactic radiosurgery: Role of quantitative MRA.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Quantitative hemodynamics of draining veins in brain arteriovenous malformation: a preliminary study based on computational fluid dynamics.Frontiers in neurology · 2024Article
- Challenges in Modeling Hemodynamics in Cerebral Aneurysms Related to Arteriovenous Malformations.Cardiovascular engineering and technology · 2022Article
- Accelerated dual-venc 4D flow MRI with variable high-venc spatial resolution for neurovascular applications.Magnetic resonance in medicine · 2022Article
- Intracranial Blood Flow Quantification by Accelerated Dual-venc 4D Flow MRI: Comparison With Transcranial Doppler Ultrasound.Journal of magnetic resonance imaging : JMRI · 2022Article
- Article
- Recent progress understanding pathophysiology and genesis of brain AVM-a narrative review.Neurosurgical review · 2021Review
- Signal intensity ratio of draining vein on silent MR angiography as an indicator of high-flow arteriovenous shunt in brain arteriovenous malformation.European radiology · 2021Article
- Article
- Experimental Assessment of Two Non-Contrast MRI Sequences Used for Computational Fluid Dynamics: Investigation of Consistency Between Techniques.Cardiovascular engineering and technology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
background and purposeArteriovenous malformations have a high lifetime risk of hemorrhage; however, treatment carries a significant risk of morbidity and mortality, including permanent neurologic sequelae. WSS and other hemodynamic parameters are altered in patients with symptomatic AVMs, and analysis of hemodynamics may have value in stratifying patients into different risk groups. In this study, we examined hemodynamic data from patients with stable symptoms and those who presented with acute symptoms to identify trends which may help in risk stratification. MATERIALS AND
methodsPhase-contrast MRA using a radial readout (PC-VIPR) is a fast, high-resolution technique that can acquire whole-brain velocity-encoded angiograms with scan times of approximately 5 minutes. Ten patients with AVMs were scanned using PC-VIPR; velocity, area, flow, and WSS in vessels feeding the AVMs and normal contralateral vessels were calculated using velocity data from the phase-contrast acquisition.
resultsPatients with an asymptomatic presentation or mild symptoms (n = 4) had no significant difference in WSS in feeding vessels compared with normal contralateral vessels, whereas patients presenting with hemorrhage, severe headaches/seizures, or focal neurologic deficits (n = 6) had significantly higher WSS in feeding vessels compared with contralateral vessels.
conclusionsIn this study, we demonstrate that estimates of WSS and other hemodynamic parameters can be obtained noninvasively in patients with AVMs in clinically useful imaging times. Variation in WSS between feeders and normal vessels appears to relate to the clinical presentation of the patient. Further analysis of hemodynamic changes may improve characterization and staging of AVM patients, when combined with existing risk factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.