ReviewThe journal of nutrition, health & aging2012
Recruitment methods for United States Alzheimer disease prevention trials.
Review in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Trial
- Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study.Alzheimer's research & therapy · 2024Article
- Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment.Alzheimer's research & therapy · 2023Article
- Recruitment across two decades of NIH-funded Alzheimer's disease clinical trials.Alzheimer's research & therapy · 2023Article
- The efficacy of mindfulness-based cognitive therapy to improve depression symptoms and quality of life in individuals with memory difficulties and caregivers: A short report.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- T2 Protect AD: Achieving a rapid recruitment timeline in a multisite clinical trial for individuals with mild to moderate Alzheimer's disease.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Mindfulness, Education, and Exercise for age-related cognitive decline: Study protocol, pilot study results, and description of the baseline sample.Clinical trials (London, England) · 2020Article
- The Alzheimer's Prevention Registry: A Large Internet-Based Participant Recruitment Registry to Accelerate Referrals to Alzheimer's-Focused Studies.The journal of prevention of Alzheimer's disease · 2020Article
- GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2019Article
- Patient Engagement: The Fundació ACE Framework for Improving Recruitment and Retention in Alzheimer's Disease Research.Journal of Alzheimer's disease : JAD · 2018Review
- Recruiting to preclinical Alzheimer's disease clinical trials through registries.Alzheimer's & dementia (New York, N. Y.) · 2017Article
- Attitudes toward Potential Participant Registries.Journal of Alzheimer's disease : JAD · 2017Article
- Recruiting Community-Based Dementia Patients and Caregivers in a Nonpharmacologic Randomized Trial: What Works and How Much Does It Cost?Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2016Article
- Obstacles and opportunities in Alzheimer's clinical trial recruitment.Health affairs (Project Hope) · 2014Article
- Alzheimer's disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology.The journal of nutrition, health & aging · 2012Article
- Mail and Telephone Outreach from Electronic Health Records for Research Participation on Cognitive Health and Aging.The journal of prevention of Alzheimer's diseaseArticle
- The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease.Alzheimer disease and associated disordersArticle
- Facilitating Alzheimer disease research recruitment.Alzheimer disease and associated disordersReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are no substantially effective treatments or preventatives for Alzheimer disease. The few prevention trials that were undertaken did not shown efficacy for the drugs tested; but, nevertheless, advanced prevention trials methods. We review past recruitment methods and discuss areas for improvement. Improvements in recruitment methods can enhance the likelihood for accurately demonstrating the efficacy of an effective drug. Effective therapeutics to prevent AD await discovery and proof.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.