Evidence map›Paper›PMID 22499096›Full record

ArticleMuscle & nerve2012

The convergence of facial nerve branches providing whisker pad motor supply in rats: implications for facial reanimation study.

Doug Henstrom, Tessa Hadlock, Robin Lindsay, Christopher J Knox, Juan Malo, Kalpesh T Vakharia, James T Heaton

Abstract read
In one paragraph

Article in Muscle & nerve, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Interchangeable Role of Motor Cortex and Reafference for the Stable Execution of an Orofacial Action.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Autonomic Nerve Fibers Aberrantly Reinnervate Denervated Facial Muscles and Alter Muscle Fiber Population.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. A system for delivering mechanical stimulation and robot-assisted therapy to the rat whisker pad during facial nerve regeneration.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Doug HenstromDepartment of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, USA.
Tessa Hadlock
Robin Lindsay
Christopher J Knox
Juan Malo
Kalpesh T Vakharia
James T Heaton

Funding

Surgical and Rehabilitative Management of Facial Nerve InjuryR01NS071067 · NINDS · MASSACHUSETTS EYE AND EAR INFIRMARY · PI HADLOCK, THERESA A · 2010 to 2020
$4.6M
NINDS NIH HHS R01 NS071067
6 · The paper itself

Abstract

introductionRodent whisking behavior is supported by the buccal and mandibular branches of the facial nerve, but a description of how these branches converge and contribute to whisker movement is lacking.

methodsEight rats underwent isolated transection of either the buccal or mandibular branch and subsequent opposite branch transection. Whisking function was analyzed after both transections. Anatomical measurements, and video recording of stimulation to individual branches, were taken from both facial nerves in 10 rats.

resultsNormal to near-normal whisking was demonstrated after isolated branch transection. Whisking was eliminated after transection of both branches. The buccal and mandibular branches form a convergence just proximal to the whisker pad, herein called "distal pes." Distal to this convergence, we identified consistent anatomy that demonstrated cross-innervation.

conclusionThe overlap of efferent supply to the whisker pad must be considered when studying facial nerve regeneration in the rat facial nerve model.

Indexed as

AnimalsDenervationElectric StimulationFacial NerveFemaleFunctional LateralityMovementRandom AllocationRatsRats, WistarVibrissaeVideo Recording

Identifiers

PMID22499096
PMCPMC4388195

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.