Evidence map›Paper›PMID 22498720›Full record

Trial reportContemporary clinical trials2012

Design and rationale for Home Blood Pressure Telemonitoring and Case Management to Control Hypertension (HyperLink): a cluster randomized trial.

Karen L Margolis, Tessa J Kerby, Stephen E Asche, Anna R Bergdall, Michael V Maciosek, Patrick J O'Connor, JoAnn M Sperl-Hillen

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00781365 (Home Blood Pressure Telemonitoring and Case Management to Control Hypertension), which is not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00781365 nacompletednot on this map

Home Blood Pressure Telemonitoring and Case Management to Control Hypertension

TypeinterventionalSponsorHealthPartners InstituteRan2009 to 2012Enrolled450ConditionsHypertensionArmsTelemonitors and pharmacy management
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  12. Adherence to blood pressure telemonitoring in a cluster-randomized clinical trial.Journal of clinical hypertension (Greenwich, Conn.) · 2012
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  20. Telemedicine and M-Health in Hypertension Management: Technologies, Applications and Clinical Evidence.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karen L MargolisHealthPartners Research Foundation, Minneapolis, MN 55440-1524, USA. Karen.l.margolis@healthpartners.com
Tessa J Kerby
Stephen E Asche
Anna R Bergdall
Michael V Maciosek
Patrick J O'Connor
JoAnn M Sperl-Hillen
HealthPartners · US

Funding

Home Blood Pressure Telemonitoring and Case Management to Control HypertensionR01HL090965 · NHLBI · HEALTHPARTNERS INSTITUTE · PI MARGOLIS, KAREN L · 2008 to 2015
$3.3M
NHLBI NIH HHS R01 HL090965NHLBI NIH HHS R01HL090965
6 · The paper itself

Abstract

backgroundPatients with high blood pressure (BP) visit a physician an average of 4 times or more per year in the U.S., yet BP is controlled in fewer than half. Practical, robust and sustainable models are needed to improve BP in patients with uncontrolled hypertension.

objectivesThe Home Blood Pressure Telemonitoring and Case Management to Control Hypertension study (HyperLink) is a cluster-randomized trial designed to determine whether an intervention that combines home BP telemonitoring with pharmacist case management improves BP control compared to usual care at 6 and 12 months in patients with uncontrolled hypertension. Secondary outcomes are maintenance of BP control at 18 months, patient satisfaction with their health care, and costs of care.

methodsHyperLink enrolled 450 hypertensive patients with uncontrolled BP from 16 primary care clinics. Eight clinics were randomized to provide usual care (UC) to their patients (n=222) and 8 were randomized to provide the telemonitoring intervention (TI) (n=228). TI patients received home BP telemonitors that internally store and electronically transmit BP data to a secure database. Pharmacist case managers adjust antihypertensive therapy based on the home BP data under a collaborative practice agreement with the clinics' primary care teams. The length of the intervention is 12 months, with follow-up to 18 months to determine the durability of the intervention.

conclusionsWe will test in a real primary care setting whether combining BP telemonitoring and pharmacist case management can achieve and maintain high rates of BP control compared to usual care.

Indexed as

Case ManagementMedication Therapy ManagementAdultAgedAged, 80 and overAntihypertensive AgentsBlood Pressure Monitoring, AmbulatoryClinical ProtocolsCost-Benefit AnalysisFollow-Up StudiesHealth Care CostsHumansHypertensionLinear ModelsMiddle AgedMinnesotaAntihypertensive Agents

Identifiers

PMID22498720
PMCPMC3361626
OpenAlexW2004890656

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.