Evidence map›Paper›PMID 22498252›Full record

ReviewBiochimica et biophysica acta2012

Small nucleolar RNAs in cancer.

Kaiissar Mannoor, Jipei Liao, Feng Jiang

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 155 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases.Virchows Archiv : an international journal of pathology · 2024
    Article
  6. Article
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  9. Review
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  13. Review
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  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. ABiomedicines · 2022
    Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kaiissar Mannoor *Department of Pathology, University of Maryland School of Medicine, 10 S, Pine St, Baltimore, MD 21201, USA.
Jipei Liao *Department of Pathology, University of Maryland School of Medicine, 10 S, Pine St, Baltimore, MD 21201, USA.
Feng JiangDepartment of Pathology, University of Maryland School of Medicine, 10 S, Pine St, Baltimore, MD 21201, USA.
University of Maryland, Baltimore · US

Funding

Non-invasive Biomarker Panels for Early Detection of Lung Squamous Cell CarcinomaR01CA161837 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI JIANG, FENG · 2011 to 2013
$998k
A Sensitive and Automated Diagnostic Assay for Lung CancerR21CA135382 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI JIANG, FENG · 2008 to 2009
$338k
New Diagnostic Assay for Early Detection of Lung CancerR21CA113707 · NCI · UNIVERSITY OF TEXAS MD ANDERSON CAN CTR · PI JIANG, FENG · 2005 to 2006
$252k
A Genetic Test for Lung Cancer Early DetectionR03CA133956 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI JIANG, FENG · 2008 to 2009
$150k
Magnetic Enrichment for Genetic Detection of Carcinoma Cells in SputumR03CA137742 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI JIANG, FENG · 2008 to 2009
$150k
NCI NIH HHS CA133956NCI NIH HHS CA135382NCI NIH HHS CA137742NCI NIH HHS CA161837NCI NIH HHS R01 CA161837NCI NIH HHS R03 CA133956NCI NIH HHS R03 CA137742NCI NIH HHS R21 CA113707NCI NIH HHS R21 CA135382
6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and cellular processes. Alterations of ncRNAs, particularly microRNAs, play crucial roles in tumorigenesis. Accumulating evidence indicates that small nucleolar RNAs (snoRNAs), another large class of small ncRNAs, are gaining prominence and more actively involved in carcinogenesis than previously thought. Some snoRNAs exhibit differential expression patterns in a variety of human cancers and demonstrate capability to affect cell transformation, tumorigenesis, and metastasis. We are beginning to comprehend the functional repercussions of snoRNAs in the development and progression of malignancy. In this review, we will describe current studies that have shed new light on the functions of snoRNAs in carcinogenesis and the potential applications for cancer diagnosis and therapy.

Indexed as

Biomarkers, TumorCell Transformation, NeoplasticHumansNeoplasmsRNA, Small NucleolarRNA, UntranslatedBiomarkers, TumorRNA, Small NucleolarRNA, Untranslated

Identifiers

PMID22498252
PMCPMC3842010
OpenAlexW2066151767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.