ArticleThe Journal of biological chemistry2012
Rhodanese functions as sulfur supplier for key enzymes in sulfur energy metabolism.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Sulfur disproportionation occurs globally across anoxic habitats and has multiple mechanisms of independent evolutionary origin.The ISME journal · 2026Review
- Isolation of a putative sulfur comproportionating microorganism.Scientific reports · 2025Article
- Array of metabolic pathways in a kleptoplastidic foraminiferan protist supports chemoautotrophy in dark, euxinic seafloor sediments.The ISME journal · 2025Article
- Plant cyanogenic glycosides: from structure to properties and potential applications.Frontiers in plant science · 2025Review
- A cascade of sulfur transferases delivers sulfur to the sulfur-oxidizing heterodisulfide reductase-like complex.Protein science : a publication of the Protein Society · 2024Article
- Persulfide Biosynthesis Conserved Evolutionarily in All Organisms.Antioxidants & redox signaling · 2023Review
- Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut.Nature communications · 2023Article
- In Situ Genomics and Transcriptomics of SAR202 Subclusters Revealed Subtle Distinct Activities in Deep-Sea Water.Microorganisms · 2022Article
- Initial Mapping of the New York City Wastewater Virome.mSystems · 2020Article
- Proteome Cold-Shock Response in the Extremely Acidophilic Archaeon,Microorganisms · 2020Article
- Omics Integration for Mitochondria Systems Biology.Antioxidants & redox signaling · 2020Review
- Crystallographic and cryogenic electron microscopic structures and enzymatic characterization of sulfur oxygenase reductase fromJournal of structural biology: X · 2020Article
- Article
- Physiology, Metabolism, and Fossilization of Hot-Spring Filamentous Microbial Mats.Astrobiology · 2019Article
- Insight into the sulfur metabolism of Desulfurella amilsii by differential proteomics.Environmental microbiology · 2019Article
- Identification of Different Putative Outer Membrane Electron Conduits Necessary for Fe(III) Citrate, Fe(III) Oxide, Mn(IV) Oxide, or Electrode Reduction by Geobacter sulfurreducens.Journal of bacteriology · 2018Article
- The enigmatic SAR202 cluster up close: shedding light on a globally distributed dark ocean lineage involved in sulfur cycling.The ISME journal · 2018Article
- Discovery of anaerobic lithoheterotrophic haloarchaea, ubiquitous in hypersaline habitats.The ISME journal · 2017Article
- In Situ Gene Expression Responsible for Sulfide Oxidation and CO2 Fixation of an Uncultured Large Sausage-Shaped Aquificae Bacterium in a Sulfidic Hot Spring.Microbes and environments · 2016Article
- Sulfurtransferase and thioredoxin specifically interact as demonstrated by bimolecular fluorescence complementation analysis and biochemical tests.FEBS open bio · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How microorganisms obtain energy is a challenging topic, and there have been numerous studies on the mechanisms involved. Here, we focus on the energy substrate traffic in the hyperthermophilic bacterium Aquifex aeolicus. This bacterium can use insoluble sulfur as an energy substrate and has an intricate sulfur energy metabolism involving several sulfur-reducing and -oxidizing supercomplexes and enzymes. We demonstrate that the cytoplasmic rhodanese SbdP participates in this sulfur energy metabolism. Rhodaneses are a widespread family of proteins known to transfer sulfur atoms. We show that SbdP has also some unusual characteristics compared with other rhodaneses; it can load a long sulfur chain, and it can interact with more than one partner. Its partners (sulfur reductase and sulfur oxygenase reductase) are key enzymes of the sulfur energy metabolism of A. aeolicus and share the capacity to use long sulfur chains as substrate. We demonstrate a positive effect of SbdP, once loaded with sulfur chains, on sulfur reductase activity, most likely by optimizing substrate uptake. Taken together, these results lead us to propose a physiological role for SbdP as a carrier and sulfur chain donor to these key enzymes, therefore enabling channeling of sulfur substrate in the cell as well as greater efficiency of the sulfur energy metabolism of A. aeolicus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.