SynthesisJAMA2012
Does this adult patient have a blunt intra-abdominal injury?
Synthesis in JAMA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04937868 (Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients), which is not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- Incidence of intra-abdominal injury after blunt abdominal trauma with negative CT scan: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2026Pooled it
- Emergency ultrasound-based algorithms for diagnosing blunt abdominal trauma.The Cochrane database of systematic reviews · 2015Pooled it
- Comparison of the diagnostic accuracy of CT scan with oral and intravenous contrast versus CT scan with intravenous contrast alone in the diagnosis of blunt abdominal trauma.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023Trial
- Trial
- Emergency surgery for blunt abdominal trauma in polytrauma - the impact of time to laparotomy on outcomes.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Article
- Rare and Unusual Consequences of Blunt Abdominal Trauma-The Significance of Anatomical Anomalies.Journal of clinical medicine · 2026Review
- Comparative outcomes of transcatheter arterial embolization versus open surgery for blunt abdominal solid organ injury with concurrent traumatic brain injury.Scientific reports · 2025Observational
- Enhancing clinical risk assessment in pediatric blunt abdominal trauma: A novel scoring system using ultrasound and laboratory data.BMC emergency medicine · 2025Article
- Immediate versus expedient emergent laparotomy in unstable isolated abdominal trauma patients.Annals of the Royal College of Surgeons of England · 2025Article
- Undetermined Ruptured Low-Grade Appendiceal Mucinous Neoplasm Following High-Energy Blunt Abdominal Trauma Requiring Emergency Laparotomy.Clinical case reports · 2025Article
- Article
- Non-therapeutic laparotomies in military trauma (2009-2014).Surgical endoscopy · 2024Article
- Article
- Article
- Prediction of intra-abdominal injury using natural language processing of electronic medical record data.Surgery · 2024Observational
- Incidence of intra-abdominal injuries in hemodynamically stable blunt trauma patients with a normal computed tomography scan admitted to the emergency department.BMC emergency medicine · 2024Article
- Contrast-enhanced point of care ultrasound for the evaluation of stable blunt abdominal trauma by the emergency physician: A prospective diagnostic study.Journal of the American College of Emergency Physicians open · 2024Article
- Multiorgan Point-of-Care Ultrasound Assessment in Critically Ill Adults.Journal of intensive care medicine · 2024Article
- Diagnosis of traumatic liver injury on computed tomography using machine learning algorithms and radiomics features: The role of artificial intelligence for rapid diagnosis in emergency rooms.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
contextBlunt abdominal trauma often presents a substantial diagnostic challenge. Well-informed clinical examination can identify patients who require further diagnostic evaluation for intra-abdominal injuries after blunt abdominal trauma.
objectiveTo systematically assess the precision and accuracy of symptoms, signs, laboratory tests, and bedside imaging studies to identify intra-abdominal injuries in patients with blunt abdominal trauma. DATA SOURCES: We conducted a structured search of MEDLINE (1950-January 2012) and EMBASE (1980-January 2012) to identify English-language studies examining the identification of intra-abdominal injuries. A separate, structured search was conducted for studies evaluating bedside ultrasonography. STUDY SELECTION: We included studies of diagnostic accuracy for intra-abdominal injury that compared at least 1 finding with a reference standard of abdominal computed tomography, diagnostic peritoneal lavage, laparotomy, autopsy, and/or clinical course for intra-abdominal injury. Twelve studies on clinical findings and 22 studies on bedside ultrasonography met inclusion criteria for data extraction. DATA EXTRACTION: Critical appraisal and data extraction were independently performed by 2 authors. DATA SYNTHESIS: The prevalence of intra-abdominal injury in adult emergency department patients with blunt abdominal trauma among all evidence level 1 and 2 studies was 13% (95% CI, 10%-17%), with 4.7% (95% CI, 2.5%-8.6%) requiring therapeutic surgery or angiographic embolization of injuries. The presence of a seat belt sign (likelihood ratio [LR] range, 5.6-9.9), rebound tenderness (LR, 6.5; 95% CI, 1.8-24), hypotension (LR, 5.2; 95% CI, 3.5-7.5), abdominal distention (LR, 3.8; 95% CI, 1.9-7.6), or guarding (LR, 3.7; 95% CI, 2.3-5.9) suggest an intra-abdominal injury. The absence of abdominal tenderness to palpation does not rule out an intra-abdominal injury (summary LR, 0.61; 95% CI, 0.46-0.80). The presence of intraperitoneal fluid or organ injury on bedside ultrasound assessment is more accurate than any history and physical examination findings (adjusted summary LR, 30; 95% CI, 20-46); conversely, a normal ultrasound result decreases the chance of injury detection (adjusted summary LR, 0.26; 95% CI, 0.19-0.34). Test results increasing the likelihood of intra-abdominal injury include a base deficit less than -6 mEq/L (LR, 18; 95% CI, 11-30), elevated liver transaminases (LR range, 2.5-5.2), hematuria (LR range, 3.7-4.1), anemia (LR range, 2.2-3.3), and abnormal chest radiograph (LR range, 2.5-3.8). Symptoms and signs may be most useful in combination, particularly in identification of patients who do not need further diagnostic workup.
conclusionsBedside ultrasonography has the highest accuracy of all individual findings, but a normal result does not rule out an intra-abdominal injury. Combinations of clinical findings may be most useful to determine which patients do not require further evaluation, but the ideal combination of variables for identifying patients without intra-abdominal injury requires further study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.