ReviewVascular medicine (London, England)2012
Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease.
Review in Vascular medicine (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between periodontitis and peripheral artery disease: a systematic review and meta-analysis.BMC cardiovascular disorders · 2018Pooled it
- Growth factors for angiogenesis in peripheral arterial disease.The Cochrane database of systematic reviews · 2017Pooled it
- [Efficacy of drug-coated balloon and common balloon for treatment of superficial femoral artery and popliteal artery arteriosclerosis obliterans: prospective randomized controlled triac].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017Trial
- Bioengineering Cell Therapy for Treatment of Peripheral Artery Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Review
- [Animal experimental study on the effects of different levels of amputation on cardiovascular system].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Target and Cell Therapy for Atherosclerosis and CVD.International journal of molecular sciences · 2023Review
- Dual-Source Photon-Counting Computed Tomography-Part III: Clinical Overview of Vascular Applications beyond Cardiac and Neuro Imaging.Journal of clinical medicine · 2023Review
- ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway.International journal of molecular medicine · 2022Article
- Periodontitis and cardiovascular disease: A literature review.ARYA atherosclerosis · 2021Review
- Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia.Iranian journal of basic medical sciences · 2021Article
- A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization.iScience · 2021Article
- The Role of miR-181c in Mechanisms of Diabetes-Impaired Angiogenesis: An Emerging Therapeutic Target for Diabetic Vascular Complications.Frontiers in pharmacology · 2021Review
- MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells.Arteriosclerosis, thrombosis, and vascular biology · 2019Article
- Enzymatically degradable alginate hydrogel systems to deliver endothelial progenitor cells for potential revasculature applications.Biomaterials · 2018Article
- Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health.Pteridines · 2018Article
- Alginate hydrogels of varied molecular weight distribution enable sustained release of sphingosine-1-phosphate and promote angiogenesis.Journal of biomedical materials research. Part A · 2018Article
- Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation.Heart and vessels · 2017Article
- Current therapies and investigational drugs for peripheral arterial disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Review
- Fabrication and characterization of injectable hydrogels derived from decellularized skeletal and cardiac muscle.Methods (San Diego, Calif.) · 2015Article
- Cell Therapy in Patients with Critical Limb Ischemia.Stem cells international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Therapeutic angiogenesis utilizing genetic and cellular modalities in the treatment of arterial obstructive diseases continues to evolve. This is, in part, because the mechanism of vasculogenesis, angiogenesis, and arteriogenesis (the three processes by which the body responds to obstruction of large conduit arteries) is a complex process that is still under investigation. To date, the majority of human trials utilizing molecular, genetic, and cellular modalities for therapeutic angiogenesis in the treatment of peripheral artery disease (PAD) have not shown efficacy. Consequently, the current available knowledge is yet to be translated into novel therapeutic approaches for the treatment of PAD. The aim of this review is to discuss relevant scientific and clinical advances in therapeutic angiogenesis and their potential application in the treatment of ischemic diseases of the peripheral arteries. Additionally, this review article discusses past and recent developments, such as some unconventional approaches that have the potential to be applied as therapeutic targets. The article also includes advances in the delivery of genetic, cellular, and bioactive endothelial growth factors.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.