ArticleThe Journal of comparative neurology2012
Connexin 57 is expressed by the axon terminal network of B-type horizontal cells in the rabbit retina.
Article in The Journal of comparative neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Extrinsic and Intrinsic Factors Determine Expression Levels of Gap Junction-Forming Connexins in the Mammalian Retina.Biomolecules · 2023Review
- Dye coupling of horizontal cells in the primate retina.Frontiers in ophthalmology · 2023Article
- Article
- Connexin-36 distribution and layer-specific topography in the cat retina.Brain structure & function · 2019Article
- Design principles of electrical synaptic plasticity.Neuroscience letters · 2019Review
- Synaptic Functions of Hemichannels and Pannexons: A Double-Edged Sword.Frontiers in molecular neuroscience · 2018Review
- Zebrafish connexin 79.8 (Gja8a): A lens connexin used as an electrical synapse in some neurons.Developmental neurobiology · 2017Article
- Membrane-associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors.The Journal of comparative neurology · 2017Article
- Horizontal Cells, the Odd Ones Out in the Retina, Give Insights into Development and Disease.Frontiers in neuroanatomy · 2016Review
- Independent losses of visual perception genes Gja10 and Rbp3 in echolocating bats (Order: Chiroptera).PloS one · 2013Article
- Variety of horizontal cell gap junctions in the rabbit retina.Neuroscience letters · 2012Article
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7 authors at 1 institution in 1 country.
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Abstract
In the rabbit retina there are two types of horizontal cell (HC). A-type HCs (AHC) are axonless and extensively coupled via connexin (Cx)50 gap junctions. The B-type HC (BHC) is axon-bearing; the somatic dendrites form a second network coupled by gap junctions while the axon terminals (ATs) form a third independent network in the outer plexiform layer (OPL). The mouse retina has only one type of HC, which is morphologically similar to the B-type HC of the rabbit. Previous work suggested that mouse HCs express Cx57 (Hombach et al. [2004] Eur J Neurosci 19:2633-2640). Therefore, we cloned rabbit Cx57 and raised an antibody to determine the distribution of Cx57 gap junctions among rabbit HCs. Dye injection methods were used to obtain detailed fills for all three HC networks for analysis by confocal microscopy. We found that Cx57 was associated with the B-type AT plexus. Cx57 plaques were anticorrelated with the B-type somatic dendrites and the A-type HC network. Furthermore, there was no colocalization between Cx50 and Cx57. We conclude that in the rabbit retina, Cx57 is only found on BHC-AT processes. Thus, in species where there are two types of HC, different connexins are expressed. The absence of Cx57 labeling in the somatic dendrites of B-type HCs suggests the possibility of an additional unidentified HC connexin in the rabbit.
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