ArticleSocial science & medicine (1982)2012
HIV and chemoprophylaxis, the importance of considering social structures alongside biomedical and behavioral intervention.
Article in Social science & medicine (1982), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of interventions to reduce HIV-related stigma and discrimination from 2002 to 2013: how far have we come?Journal of the International AIDS Society · 2013Pooled it
- Evaluation of Sexual Risk Behavior Among Study Participants in the TDF2 PrEP Study Among Heterosexual Adults in Botswana.Journal of acquired immune deficiency syndromes (1999) · 2016Trial
- Participant experiences and facilitators and barriers to pill use among men who have sex with men in the iPrEx pre-exposure prophylaxis trial in San Francisco.AIDS patient care and STDs · 2013Trial
- Retention of clients in HIV oral pre-exposure prophylaxis care in Engela, Namibia.African journal of primary health care & family medicine · 2025Article
- Ryan White programming that primarily supports clinical care falls short when core people needs are not met: further evidence from the medical monitoring project.AIDS (London, England) · 2022Article
- Ambivalence and the biopolitics of HIV pre-exposure prophylaxis (PrEP) implementation.Social theory & health : STH · 2022Article
- Article
- A synthesis of implementation science frameworks and application to global health gaps.Global health research and policy · 2019Article
- Overcoming HIV Stigma? A Qualitative Analysis of HIV Cure Research and Stigma Among Men Who Have Sex with Men Living with HIV.Archives of sexual behavior · 2018Article
- Use of 'eradication' in HIV cure-related research: a public health debate.BMC public health · 2018Article
- Stigma, Partners, Providers and Costs: Potential Barriers to PrEP Uptake among US Women.Journal of AIDS & clinical research · 2017Article
- Risk, reassurance and routine: a qualitative study of narrative understandings of the potential for HIV self-testing among men who have sex with men in England.BMC public health · 2017Article
- Expanding the knowledge translation metaphor.Health research policy and systems · 2017Article
- How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis and treatment as prevention.AIDS and behavior · 2014Review
- Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection.International journal of clinical pharmacy · 2014Review
- Evaluating social outcomes of HIV/AIDS interventions: a critical assessment of contemporary indicator frameworks.Journal of the International AIDS Society · 2014Review
- Exploring the influence of social determinants on HIV risk behaviors and the potential application of structural interventions to prevent HIV in women.Journal of health disparities research and practice · 2014Article
- PrEP awareness and perceived barriers among single young men who have sex with men.Current HIV research · 2013Article
- Microbicide clinical trial adherence: insights for introduction.Journal of the International AIDS Society · 2013Review
- A typology of structural approaches to HIV prevention: a commentary on Roberts and Matthews.Social science & medicine (1982) · 2012Article
Corrections and comments
- Commented on by
Authors and funding
2 authors.
Funding
Abstract
This manuscript draws connections between chemoprophylaxis and the biomedical model of disease that emphasizes individual behavior. We argue that chemoprophylactic HIV interventions have limited utility at the population-level, and that structural interventions need to be prioritized. We use the recent CAPRISA 004 and iPrEx trials to (a) critique the utility of these trials from a public health perspective by highlighting the difference between efficacy and effectiveness, (b) apply an alternative theory of health behavior as a way to reorient the field toward the discussion of the need to employ structural interventions, and (c) examine two aspects of HIV prevention efforts - funding structures and iatrogenic effects of biomedical approaches - as a means of overcoming obstacles to more widespread adoption of structural interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.