Evidence map›Paper›PMID 22494658›Full record

ArticleJournal of vascular and interventional radiology : JVIR2012

Cone-beam computed tomography fusion and navigation for real-time positron emission tomography-guided biopsies and ablations: a feasibility study.

Nadine Abi-Jaoudeh, Peter Mielekamp, Niels Noordhoek, Aradhana M Venkatesan, Corina Millo, Alessandro Radaelli, Bart Carelsen, Bradford J Wood

Abstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Role of Fusion Imaging in Image-Guided Thermal Ablations.Diagnostics (Basel, Switzerland) · 2021
    Review
  5. Comparison Between CBCT and Fusion PET/CT-CBCT Guidance for Lung Biopsies.Cardiovascular and interventional radiology · 2021
    Observational
  6. State of the Art: Toward Improving Outcomes of Lung and Liver Tumor Biopsies in Clinical Trials-A Multidisciplinary Approach.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Article
  7. Article
  8. Paediatric musculoskeletal interventional radiology.The British journal of radiology · 2016
    Review
  9. Clinical experience with cone-beam CT navigation for tumor ablation.Journal of vascular and interventional radiology : JVIR · 2015
    Article
  10. Review
  11. Image-guided nerve cryoablation for post-thoracotomy pain syndrome.Cardiovascular and interventional radiology · 2014
    Article
  12. Article
  13. Image fusion during vascular and nonvascular image-guided procedures.Techniques in vascular and interventional radiology · 2013
    Review
  14. Biopsy and personalized medicine.Nature reviews. Gastroenterology & hepatology · 2012
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadine Abi-JaoudehDepartment of Radiology and Imaging Sciences, National Institutes of Health, Bethesda MD 20892, USA. naj@mail.nih.gov
Peter Mielekamp
Niels Noordhoek
Aradhana M Venkatesan
Corina Millo
Alessandro Radaelli
Bart Carelsen
Bradford J Wood

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Navigation Tools for Image Guided Minimally invasive TherapiesZIACL040011 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
Interventional OncologyZIACL040015 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
CLC NIH HHS 1Z01CL046011-01Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

purposeTo describe a novel technique for multimodality positron emission tomography (PET) fusion-guided interventions that combines cone-beam computed tomography (CT) with PET/CT before the procedure. MATERIALS AND

methodsSubjects were selected among patients scheduled for a biopsy or ablation procedure. The lesions were not visible with conventional imaging methods or did not have uniform uptake on PET. Clinical success was defined by adequate histopathologic specimens for molecular profiling or diagnosis and by lack of enhancement on follow-up imaging for ablation procedures. Time to target (time elapsed between the completion of the initial cone-beam CT scan and first tissue sample or treatment), total procedure time (time from the moment the patient was on the table until the patient was off the table), and number of times the needle was repositioned were recorded.

resultsSeven patients underwent eight procedures (two ablations and six biopsies). Registration and procedures were completed successfully in all cases. Clinical success was achieved in all biopsy procedures and in one of the two ablation procedures. The needle was repositioned once in one biopsy procedure only. On average, the time to target was 38 minutes (range 13-54 min). Total procedure time was 95 minutes (range 51-240 min, which includes composite ablation). On average, fluoroscopy time was 2.5 minutes (range 1.3-6.2 min).

conclusionsAn integrated cone-beam CT software platform can enable PET-guided biopsies and ablation procedures without the need for additional specialized hardware.

Indexed as

Cone-Beam Computed TomographyMultimodal ImagingPositron-Emission TomographyRadiography, InterventionalTomography, X-Ray ComputedAgedAged, 80 and overBiopsy, NeedleCatheter AblationFeasibility StudiesFemaleHumansMaleMiddle AgedNeoplasmsPredictive Value of Tests

Identifiers

PMID22494658
PMCPMC3360836

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.