Evidence map›Paper›PMID 22494449›Full record

Observational studyInternational wound journal2013

Multicentre prospective observational study on professional wound care using honey (Medihoney™).

Bahram Biglari, Arash Moghaddam, Kai Santos, Gisela Blaser, Axel Büchler, Gisela Jansen, Alfred Längler, Norbert Graf, Ursula Weiler, Verena Licht and 8 more

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International wound journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 51 citations in OpenAlex.

  1. Observational
  2. Honey as a Natural Antimicrobial.Antibiotics (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Ulcerated tophaceous gout.BMJ case reports · 2015
    Article
  12. Review
  13. Up-to-date use of honey for burns treatment.Annals of burns and fire disasters · 2014
    Review
  14. Article
  15. Evaluation of the effects of honey on acute-phase deep burn wounds.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 3 countries.

Bahram BiglariDepartment of Paraplegia and Technical Orthopaedics, Insurance Association Trauma Centre, 67071 Ludwigshafen, Germany. bbiglari@bgu-ludwigshafen.de
Arash Moghaddam
Kai Santos
Gisela Blaser
Axel Büchler
Gisela Jansen
Alfred Längler
Norbert Graf
Ursula Weiler
Verena Licht
Anke Strölin
Brigitta Keck
Volker Lauf
Udo Bode
Tyler Swing
Ralph Hanano
Nicolas T Schwarz
Arne Simon
Boston Children's Hospital · USAsklepios Klinik Sankt Augustin · DEDüsseldorf University Hospital · DEFriedrich-Ebert-Krankenhaus · DEGemeinschaftskrankenhaus Herdecke · DEHeidelberg University · DELudwigshafen University of Business and Society · DESaarland University · DESt Anna Children's Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the treatment of wounds with honey has received an increasing amount of attention from healthcare professionals in Germany and Austria. We conducted a prospective observational multicentre study using Medihoney™ dressings in 10 hospitals - nine in Germany and one in Austria. Wound-associated parameters were monitored systematically at least three times in all patients. Data derived from the treatment of 121 wounds of various aetiologies over a period of 2 years were analysed. Almost half of the patients were younger than 18 years old, and 32% of the study population was oncology patients. Overall, wound size decreased significantly during the study period and many wounds healed after relatively short time periods. Similarly, perceived pain levels decreased significantly, and the wounds showed noticeably less slough/necrosis. In general, our findings show honey to be an effective and feasible treatment option for professional wound care. In addition, our study showed a relationship between pain and slough/necrosis at the time of recruitment and during wound healing. Future comparative trials are still needed to evaluate the extent to which the positive observations made in this and other studies can definitely be attributed to the effects of honey in wound care.

Indexed as

BandagesHoneyWound HealingAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleMiddle AgedProspective Studies

Identifiers

PMID22494449
PMCPMC7950896
OpenAlexW2010781262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.