ArticleProceedings of the National Academy of Sciences of the United States of America2012
Interfacial electronic effects in functional biolayers integrated into organic field-effect transistors.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 113 citations in OpenAlex.
- Myelin-Proteinoids Interactions in Neural Signaling.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Microstructural Control of Soluble Acene Crystals for Field-Effect Transistor Gas Sensors.Nanomaterials (Basel, Switzerland) · 2022Review
- Electrolyte-gated transistors for enhanced performance bioelectronics.Nature reviews. Methods primers · 2021Article
- Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic.Materials today. Chemistry · 2020Article
- Review
- Electronic control of H+ current in a bioprotonic device with carbon nanotube porins.PloS one · 2019Article
- A Study on the Stability of Water-Gated Organic Field-Effect-Transistors Based on a Commercial p-Type Polymer.Frontiers in chemistry · 2019Article
- Electronic control of HNature communications · 2016Article
- Organic bioelectronics probing conformational changes in surface confined proteins.Scientific reports · 2016Article
- Ultraflexible organic amplifier with biocompatible gel electrodes.Nature communications · 2016Article
- Capacitance-modulated transistor detects odorant binding protein chiral interactions.Nature communications · 2015Article
- Electrochemical processes and mechanistic aspects of field-effect sensors for biomolecules.Journal of materials chemistry. C · 2015Article
- H+-type and OH- -type biological protonic semiconductors and complementary devices.Scientific reports · 2013Article
- Flexible polymer transistors with high pressure sensitivity for application in electronic skin and health monitoring.Nature communications · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biosystems integration into an organic field-effect transistor (OFET) structure is achieved by spin coating phospholipid or protein layers between the gate dielectric and the organic semiconductor. An architecture directly interfacing supported biological layers to the OFET channel is proposed and, strikingly, both the electronic properties and the biointerlayer functionality are fully retained. The platform bench tests involved OFETs integrating phospholipids and bacteriorhodopsin exposed to 1-5% anesthetic doses that reveal drug-induced changes in the lipid membrane. This result challenges the current anesthetic action model relying on the so far provided evidence that doses much higher than clinically relevant ones (2.4%) do not alter lipid bilayers' structure significantly. Furthermore, a streptavidin embedding OFET shows label-free biotin electronic detection at 10 parts-per-trillion concentration level, reaching state-of-the-art fluorescent assay performances. These examples show how the proposed bioelectronic platform, besides resulting in extremely performing biosensors, can open insights into biologically relevant phenomena involving membrane weak interfacial modifications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.