Evidence map›Paper›PMID 22493074›Full record

ArticleHypertension (Dallas, Tex. : 1979)2012

Adipose and height growth through childhood and blood pressure status in a large prospective cohort study.

Alexander Jones, Marietta Charakida, Emanuela Falaschetti, Aroon D Hingorani, Nicholas Finer, Stefano Masi, Ann E Donald, Debbie A Lawlor, George Davey Smith, John E Deanfield

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  5. Subtyping Patients With Chronic Disease Using Longitudinal BMI Patterns.IEEE journal of biomedical and health informatics · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Maternal and gestational influences on childhood blood pressure.Pediatric nephrology (Berlin, Germany) · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The value of hip circumference/heightScientific reports · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alexander JonesVascular Physiology Unit, University College London Institute of Cardiovascular Science, London, UK. alex.jones@ucl.ac.uk
Marietta Charakida
Emanuela Falaschetti
Aroon D Hingorani
Nicholas Finer
Stefano Masi
Ann E Donald
Debbie A Lawlor
George Davey Smith
John E Deanfield
British Heart Foundation · GBUniversity College London · GB

Funding

British Heart Foundation FS/05/125British Heart Foundation RG/10/004/28240Department of HealthMedical Research Council G0600705Wellcome Trust 092731
6 · The paper itself

Abstract

Raised blood pressure (BP) is the world's leading mortality risk factor. Childhood BP substantially predicts adult levels, and although both prenatal and postnatal growth influence it, their relative importance is debated. In a longitudinal study (Avon Longitudinal Study of Parents and Children) of 12 962 healthy children, we aimed to assess the relative contribution of different growth periods and of standardized measures of height versus weight-for-height (an adiposity marker) to BP at age 10 years. Conditional growth modeling was used in the 3230 boys and 3346 girls with BP measurements. Systolic BP was inversely associated with birth weight and weight-for-height but not length (-0.33, -0.27, and -0.12 mm Hg · SD(-1); P=0.003, 0.035, and 0.35, respectively). In infancy, weight, weight-for-height, and height gains were all positively associated with systolic BP (0.90, 0.41, and 0.82 mm Hg · SD(-1), respectively; all P<0.001). After infancy, all of the growth modalities were positively associated with systolic BP (weight, 1.91; weight-for-height, 1.56; height, 1.20 mm Hg · SD(-1); all P<0.001). Similar but weaker associations were found with diastolic BP. Although BP at 10 years was associated with both prenatal and early postnatal growth, their influence was small compared with that of later growth. Because BP ranking relative to the population is substantially determined in the first decade of life, a focus on strategies to reduce the development of adiposity from infancy onward, rather than an emphasis on the nutrition and weight of mothers and infants, should bring greater reductions in population BP.

Indexed as

Body HeightBody WeightAdiposityAge DistributionBirth WeightBlood Pressure DeterminationChildChild DevelopmentChild, PreschoolCohort StudiesFemaleHumansHypertensionInfantInfant, NewbornLinear Models

Identifiers

PMID22493074
PMCPMC3428923
OpenAlexW2114822892

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.