Evidence map›Paper›PMID 22493050›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2012

Unified Medical Language System term occurrences in clinical notes: a large-scale corpus analysis.

Stephen T Wu, Hongfang Liu, Dingcheng Li, Cui Tao, Mark A Musen, Christopher G Chute, Nigam H Shah

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Empirical advances with text mining of electronic health records.BMC medical informatics and decision making · 2017
    Article
  10. Article
  11. Article
  12. Androgen Deprivation Therapy and Future Alzheimer's Disease Risk.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen T WuDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA. wu.stephen@mayo.edu
Hongfang Liu
Dingcheng Li
Cui Tao
Mark A Musen
Christopher G Chute
Nigam H Shah

Funding

STANFORD COMPOSITE(RMI)U54HG004028 · NHGRI · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2005 to 2014
$36.2M
Natural language processing for clinical and translational researchR01GM102282 · NIGMS · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, PAKHOMOV, SERGUEI VS · 2013 to 2016
$2.5M
Onto-BioThesaurus: ontological representation of gene/protein names for biomedicaR01LM009959 · NLM · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG · 2009 to 2010
$1.2M
NHGRI NIH HHS U54 HG004028NIGMS NIH HHS R01 GM102282NLM NIH HHS R01 LM009959NLM NIH HHS R01LM009959A1
6 · The paper itself

Abstract

objectiveTo characterise empirical instances of Unified Medical Language System (UMLS) Metathesaurus term strings in a large clinical corpus, and to illustrate what types of term characteristics are generalisable across data sources.

designBased on the occurrences of UMLS terms in a 51 million document corpus of Mayo Clinic clinical notes, this study computes statistics about the terms' string attributes, source terminologies, semantic types and syntactic categories. Term occurrences in 2010 i2b2/VA text were also mapped; eight example filters were designed from the Mayo-based statistics and applied to i2b2/VA data.

resultsFor the corpus analysis, negligible numbers of mapped terms in the Mayo corpus had over six words or 55 characters. Of source terminologies in the UMLS, the Consumer Health Vocabulary and Systematized Nomenclature of Medicine-Clinical Terms (SNOMED-CT) had the best coverage in Mayo clinical notes at 106426 and 94788 unique terms, respectively. Of 15 semantic groups in the UMLS, seven groups accounted for 92.08% of term occurrences in Mayo data. Syntactically, over 90% of matched terms were in noun phrases. For the cross-institutional analysis, using five example filters on i2b2/VA data reduces the actual lexicon to 19.13% of the size of the UMLS and only sees a 2% reduction in matched terms.

conclusionThe corpus statistics presented here are instructive for building lexicons from the UMLS. Features intrinsic to Metathesaurus terms (well formedness, length and language) generalise easily across clinical institutions, but term frequencies should be adapted with caution. The semantic groups of mapped terms may differ slightly from institution to institution, but they differ greatly when moving to the biomedical literature domain.

Indexed as

Electronic Health RecordsNatural Language ProcessingUnified Medical Language SystemAlgorithmsSemanticsVocabulary, Controlled

Identifiers

PMID22493050
PMCPMC3392861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.