SynthesisCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2012
Body mass index and colon cancer screening: a systematic review and meta-analysis.
Synthesis in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Colorectal cancer association with metabolic syndrome and its components: a systematic review with meta-analysis.Endocrine · 2013Pooled it
- Prospective investigation of body mass index, colorectal adenoma, and colorectal cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013Trial
- Opportunities for General Internal Medicine to Promote Equity in Obesity Care.Journal of general internal medicine · 2025Article
- Article
- Survivorship care plans and adherence to breast and cervical cancer screening guidelines among cancer survivors in a national sample.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Obesity and cancer stem cells: Roles in cancer initiation, progression and therapy resistance.World journal of stem cells · 2023Review
- Lower Utilization of Colorectal Cancer Screening Among Vegetarians, Adventist Health Study-2.Journal of cancer education : the official journal of the American Association for Cancer Education · 2022Article
- Efficacy and tolerability of colonoscopies in overweight and obese patients: Results from a national database on gastrointestinal endoscopic outcomes.Endoscopy international open · 2022Article
- FABP4 in obesity-associated carcinogenesis: Novel insights into mechanisms and therapeutic implications.Frontiers in molecular biosciences · 2022Review
- Colorectal cancer risk based on extended family history and body mass index.Genetic epidemiology · 2020Article
- FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport.Cancer cell international · 2020Article
- A Comparative Study Evaluating the Incidence of Colorectal Neoplasia(s) in Candidates for Bariatric Surgery by Screening Colonoscopy, 40-49 Versus 50-65 Years Old: a Preliminary Study.Obesity surgery · 2019Article
- Metabolic syndrome and gastrointestinal cancers.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019Article
- Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments.Nature reviews. Gastroenterology & hepatology · 2018Review
- NCAPH plays important roles in human colon cancer.Cell death & disease · 2017Article
- Major Protein of Carcinoembryonic Antigen Gene Family - CD66c, A Novel Marker in Colon Carcinoma.Journal of clinical and diagnostic research : JCDR · 2016Article
- Time to Colonoscopy after Positive Fecal Blood Test in Four U.S. Health Care Systems.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Article
- Do recent epidemiologic observations impact who and how we should screen for CRC?Digestive diseases and sciences · 2015Review
- The risk of colonic adenomas and colonic cancer in obesity.Best practice & research. Clinical gastroenterology · 2014Review
- Patterns of colorectal cancer screening uptake in newly eligible men and women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundObesity is associated with increased colon cancer mortality and lower rates of mammography and Pap testing.
methodsWe conducted a systematic review to determine whether obesity is associated with lower rates of colon cancer screening. We searched the PubMed, CINAHL, and Cochrane Library databases. Two investigators reviewed citations, abstracts, and articles independently. Two investigators abstracted study information sequentially and evaluated quality independently using standardized forms. We included all studies in our qualitative syntheses. We used random effects meta-analyses to combine those studies providing screening results by the following body mass index (BMI) categories: Normal, 18.5-24.9 kg/m(2) (reference); overweight, 25-29.9 kg/m(2); class I obesity, 30-34.9 kg/m(2); class II obesity, 35-39.9 kg/m(2); and class III obesity, ≥ 40 kg/m(2).
resultsOf 5,543 citations, we included 23 articles. Almost all studies were cross-sectional and ascertained BMI and screening through self-report. BMI was not associated with colon cancer screening overall. The subgroup of obese white women reported lower rates of colon cancer screening compared with those with a normal BMI with combined ORs (95% CI) of 0.87 (0.82-0.93), 0.80 (0.65-0.99), and 0.73 (0.58-0.94) for class I, II, and III obesity, respectively. Results were similar among white men with class II obesity.
conclusionsOverall, BMI was not associated with colon cancer screening. Obese white men and women may be less likely to undergo colon cancer screening compared with those with a normal BMI. IMPACT: Further investigation of this disparity may reduce the risk of obesity-related colon cancer death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.