ReviewEndocrinology2012
A half-truth is a whole lie: on the necessity of investigating sex influences on the brain.
Review in Endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Acute stress impairs cognitive flexibility in men, not women.Stress (Amsterdam, Netherlands) · 2016Trial
- Sex-Dependent Phenotypic and Histomorphometric Biomarkers in the APPswe/PS1dE9/Blg Mouse Model of Alzheimer's Disease.Brain sciences · 2025Article
- Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases.F1000Research · 2024Article
- Age and sex effects on paired-pulse suppression and prepulse inhibition of auditory evoked potentials.Frontiers in neuroscience · 2024Article
- Sex Differences in Autism Spectrum Disorder: Diagnostic, Neurobiological, and Behavioral Features.Frontiers in psychiatry · 2022Review
- The Role of Brain Activity in Characterizing Successful Reading Intervention in Children With Dyslexia.Frontiers in neuroscience · 2022Article
- Hypothalamic-Pituitary-Adrenal Axis Activity in Childhood Predicts Emotional Memory Effects and Related Neural Circuitry in Adolescent Girls.Journal of cognitive neuroscience · 2021Article
- Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning.Neuroscience and biobehavioral reviews · 2019Review
- Neurobiological Sex Differences in Developmental Dyslexia.Frontiers in psychology · 2018Article
- Sex differences in equiprobable auditory Go/NoGo task: effects on N2 and P3.Experimental brain research · 2017Article
- The Relevance of Sex Differences in Performance Fatigability.Medicine and science in sports and exercise · 2016Review
- Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory.Molecular psychiatry · 2016Article
- Cortisol effects on fear memory reconsolidation in women.Psychopharmacology · 2016Article
- Androgens Enhance Male Urinary Tract Infection Severity in a New Model.Journal of the American Society of Nephrology : JASN · 2016Article
- Exposure to acute stress enhances decision-making competence: Evidence for the role of DHEA.Psychoneuroendocrinology · 2016Article
- Sex differences in conditioned stimulus discrimination during context-dependent fear learning and its retrieval in humans: the role of biological sex, contraceptives and menstrual cycle phases.Journal of psychiatry & neuroscience : JPN · 2015Article
- Sex differences in 3,4-methylenedioxypyrovalerone (MDPV)-induced taste avoidance and place preferences.Pharmacology, biochemistry, and behavior · 2015Article
- Investigation of pre-pubertal sex differences in wheel running and social behavior in three mouse strains.Journal of ethology · 2015Article
- Is It Important to Consider Sex and Gender in Neurocognitive Studies?Frontiers in psychiatry · 2015Review
- Reconceptualizing sex, brain and psychopathology: interaction, interaction, interaction.British journal of pharmacology · 2014Review
Corrections and comments
- Commented on by
Authors and funding
1 author.
Funding
Abstract
Sex influences are proving to be extremely widespread on brain function, including the human brain. Ample evidence now proves that the sex of subjects can influence, ever reverse, findings, hence conclusions, at all levels of brain science, down to the molecular level, often in completely unanticipated ways. Thus the still-prominent assumption that sex influences may be safely ignored by neurobiologists is invalid and must be abandoned. The failure to properly consider the issue fills the literature with conclusions tenuous at best, false at worst. The continuing, widespread resistance to investigating sex influences among brain scientists, a resistance largely rooted in deeply entrenched biases against the topic, is becoming increasingly scientifically indefensible and strongly retards progress in our field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.