Evidence map›Paper›PMID 22492025›Full record

ReviewJournal of cardiovascular translational research2012

A review of genetics, arterial stiffness, and blood pressure in African Americans.

Jennifer L Hall, Daniel A Duprez, Ana Barac, Stephen S Rich

Abstract readReview
In one paragraph

Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. New Markers of Carotid Thickening in Hypertension.Arquivos brasileiros de cardiologia · 2021
    Article
  3. Racial disparities in cardiovascular disease risk: mechanisms of vascular dysfunction.American journal of physiology. Heart and circulatory physiology · 2019
    Review
  4. Genetics of Hypertension in African Americans and Others of African Descent.International journal of molecular sciences · 2019
    Review
  5. Article
  6. Article
  7. Hypertension in African Americans.Current cardiology reports · 2017
    Review
  8. Review
  9. Observational
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jennifer L HallDivision of Cardiology, Department of Medicine, Lillehei Heart Institute, University of Minnesota, 4-106 NHH, 312 Church Street, Minneapolis, MN 55455, USA. jlhall@umn.edu
Daniel A Duprez
Ana Barac
Stephen S Rich
Minneapolis Heart Institute Foundation · USMedStar Heart & Vascular Institute · USUniversity of Virginia · US

Funding

The Role of Heparan Sulfate in Vascular RemodelingR01HL081715 · NHLBI · UNIVERSITY OF MINNESOTA · PI HALL, JENNIFER L · 2007 to 2011
$1.9M
Genetic Risk Factors of Myocyte Contractility in Human Heart FailureR21HL104596 · NHLBI · UNIVERSITY OF MINNESOTA · PI HALL, JENNIFER L · 2011 to 2012
$421k
NHLBI NIH HHS R01 HL081715NHLBI NIH HHS R21 HL104596
6 · The paper itself

Abstract

The prevalence of hypertension in African Americans in the USA is among the highest in the world and increasing. The identification of genes and pathways regulating blood pressure in African Americans has been challenging. An early predictor of hypertension is arterial stiffness. The prevalence of arterial stiffness is significantly higher in African Americans compared to Caucasians. Approximately 20 % of the variance in arterial stiffness is estimated to be heritable. Identifying genes and biological pathways regulating arterial stiffness may provide insight into the genetics underlying the increased risk of hypertension in African Americans. This paper reviews the genetic findings to date in the area of arterial stiffness and blood pressure in African Americans with an emphasis on the current limitations and new efforts to move the field forward.

Indexed as

ArteriesBlack or African AmericanBlood PressureComplianceGenetic Predisposition to DiseaseHeredityHumansHypertensionPhenotypePrevalenceRisk AssessmentRisk FactorsUnited States

Identifiers

PMID22492025
PMCPMC3381797
OpenAlexW2087461939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.