Evidence map›Paper›PMID 22491874›Full record

ArticleJournal of bone and mineral metabolism2012

An altered hormonal profile and elevated rate of bone loss are associated with low bone mass in professional horse-racing jockeys.

Eimear Dolan, Adrian McGoldrick, Colin Davenport, Grainne Kelleher, Brendan Byrne, William Tormey, Diarmuid Smith, Giles D Warrington

Abstract read
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In one paragraph

Article in Journal of bone and mineral metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  15. Nutrition and Athlete Bone Health.Sports medicine (Auckland, N.Z.) · 2019
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  19. Bone density and body composition in newly licenced professional jockeys.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Eimear DolanSchool of Health Sciences, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7QG, Scotland, UK. e.dolan@rgu.ac.uk
Adrian McGoldrick
Colin Davenport
Grainne Kelleher
Brendan Byrne
William Tormey
Diarmuid Smith
Giles D Warrington
Beaumont Hospital · IEDublin City University · IEIrish Horseracing Regulatory Board (Ireland) · IERobert Gordon University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Horse-racing jockeys are a group of weight-restricted athletes, who have been suggested as undertaking rapid and extreme weight cycling practices in order to comply with stipulated body-mass standards. The aim of this study was to examine bone mass, turnover and endocrine function in jockeys and to compare this group with age, gender and body mass index matched controls. Twenty male professional jockeys and 20 healthy male controls participated. Dual energy X-ray absorptiometry scans and early morning fasting blood and urine samples were used to measure bone mass, turnover and a hormonal profile. Total body bone mineral density (BMD) was significantly lower in jockeys (1.143 ± 0.05 vs. 1.27 ± 0.06 g cm(-3), p < 0.01). Bone resorptive activity was elevated in the jockey group as indicated by significantly higher urinary NTx/creatinine (76.94 ± 29.52 vs. 55.9 ± 13.9 nmol mmol(-1), p < 0.01), resulting in a significantly negative uncoupling index between bone resorption and formation. Sex hormone binding globulin (SHBG) levels were significantly higher in jockeys (41.21 ± 9.77 vs. 28.24 ± 9.98 nmol L(-1), p < 0.01) with a lower percentage of bioavailable testosterone (48.89 ± 7.38 vs. 59.18 ± 6.74 %, p < 0.01). SHBG and insulin-like growth factor-1 were independent predictors of total body and femoral neck BMD, respectively (p < 0.05). In conclusion, it appears that professional jockeys have an elevated rate of bone loss and reduced bone mass that appears to be associated with disrupted hormonal activity. It is likely that this may have occurred in response to the chronic weight cycling habitually experienced by this group.

Indexed as

AthletesSportsAbsorptiometry, PhotonAdultAnimalsBody CompositionBody Mass IndexBone DensityBone ResorptionCreatinineFemur NeckHormonesHorsesHumansInsulin-Like Growth Factor IMaleCreatinineHormonesInsulin-Like Growth Factor ISex Hormone-Binding GlobulinTestosterone

Identifiers

PMID22491874
OpenAlexW2119972171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.