ArticleInternational urogynecology journal2012
Alterations of heart rate variability in women with overactive bladder syndrome.
Article in International urogynecology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02456441 (The Effects of Transcutaneous Tibial Nerve Stimulation in Sympathetic and Parasympathetic System in Women With Overactive Bladder), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Transcutaneous Tibial Nerve Stimulation in Sympathetic and Parasympathetic System in Women With Overactive Bladder: Randomized Clinical Trial
Who cites it
14 citing papers in PubMed.
- Autonomic nervous system and endocrine system response to upper or lower cervical spine mobilization in males with persistent post-concussion symptoms: a proof-of-concept trial.The Journal of manual & manipulative therapy · 2024Trial
- Time-Series Analysis of Detrusor Pressure as an Adjunctive Parameter for Diagnosing Bladder Outlet Obstruction in Men.International neurourology journal · 2026Article
- Combination of skin sympathetic nerve activity and urine biomarkers in improving diagnostic accuracy for urge urinary incontinence.Scientific reports · 2025Article
- The importance of multimodal diagnostic methods for therapeutic decision making for overactive bladder in women.Medicine and pharmacy reports · 2025Review
- Applying natural language processing to understand symptoms among older adult home healthcare patients with urinary incontinence.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2025Article
- Higher skin sympathetic nerve activity as a potential predictor of overactive bladder in females refractory to oral monotherapy.The Kaohsiung journal of medical sciences · 2024Article
- Changes in Autonomic Nervous System Activity in Children With Spina Bifida: A Case-Control Study.International neurourology journal · 2023Article
- Skin sympathetic nerve activity as a potential biomarker for overactive bladder.World journal of urology · 2023Article
- Normative values of resting heart rate variability in young male contact sport athletes: Reference values for the assessment and treatment of concussion.Frontiers in sports and active living · 2022Article
- Effects of biofeedback-based sleep improvement program on urinary symptoms and sleep patterns of elderly Korean women with overactive bladder syndrome.BMC urology · 2019Article
- Prevalence of Domestic Violence in Hong Kong Chinese Women Presenting with Urinary Symptoms.PloS one · 2016Article
- The correlation between the treatment efficacy and the sympathetic activity in men with lower urinary tract symptoms.International neurourology journal · 2014Article
- Everything Hertz: methodological issues in short-term frequency-domain HRV.Frontiers in physiology · 2014Review
- Comorbidities of community-dwelling older adults with urinary incontinence: A scoping review.Geriatric nursing (New York, N.Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisOur objective was to compare autonomic nervous system function between women with an overactive bladder (OAB) and control participants during regulated bladder filling.
methodsTwenty-four women, nine with OAB and 15 without (control), were instructed to drink 1.5 l of water at a rate of 250 ml every 5 min during continuous electrocardiogram (ECG) monitoring. Participants were asked to indicate first sensations of filling (FSF), first desire to void (FDV), strong desire to void (SDV), and maximal bladder capacity (MC). ECG signals were used to assess heart rate variability, which were analyzed in time and frequency domains using the fast Fourier transform. The low-frequency (LF)and high-frequency (HF) spectral bands were used to asses sympathetic and parasympathetic pathways, respectively.
resultsDuring the bladder-filling phase, women with OAB had significantly lower LF values (at the MC phase 5.4 ± 1.4 ms(2)/Hz vs. 6.4 ± 0.6 ms(2)/Hz in the control group, p = 0.02). In the control group, LF increased continuously, whereas in the OAB group, LF increased until the sensation of SDV and then abruptly decreased to baseline values. MC was lower in women with OAB (372 ± 153 ml vs. 592 ± 298 ml, p < 0.05, respectively).
conclusionsReduced sympathetic tone in women with OAB may explain their attainment of lower volumes of MC and their sensation of urgency. The rapid decrease in sympathetic neural activity that accompanies the sensation of an SDV may be related to the pathophysiology of the urgency symptom in these women.
Indexed as
Identifiers
22491716What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.