ArticleAntimicrobial agents and chemotherapy2012
"tet(U)" is not a tetracycline resistance determinant.
Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Prediction of Antimicrobial Resistance in Clinical Enterococcus faecium Isolates Using a Rules-Based Analysis of Whole-Genome Sequences.Antimicrobial agents and chemotherapy · 2022Article
- Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 12:EFSA journal. European Food Safety Authority · 2021Article
- Genomic Relatedness, Antibiotic Resistance and Virulence Traits ofFrontiers in microbiology · 2021Article
- Antimicrobial Resistance Gene Detection and Plasmid Typing Among Multidrug Resistant Enterococci Isolated from Freshwater Environment.Microorganisms · 2020Article
- Natural Products as Platforms To Overcome Antibiotic Resistance.Chemical reviews · 2017Review
- Mosaic tetracycline resistance genes encoding ribosomal protection proteins.The Journal of antimicrobial chemotherapy · 2016Review
- Genomic Features and Niche-Adaptation of Enterococcus faecium Strains from Korean Soybean-Fermented Foods.PloS one · 2016Article
- Genetic mechanisms of antimicrobial resistance identified in Salmonella enterica, Escherichia coli, and Enteroccocus spp. isolated from U.S. food animals.Frontiers in microbiology · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The enterococcal plasmid pKQ10 has been reported to carry a poorly characterized tetracycline resistance determinant designated tet(U). However, in a series of studies intended to further characterize this determinant, we have been unable to substantiate the claim that tet(U) confers resistance to tetracyclines. In line with these results, bioinformatic analysis provides compelling evidence that "tet(U)" is in fact the misannotated 3' end of a gene encoding a rolling-circle replication initiator (Rep) protein.
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Registered trials
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