Trial reportThe journal of trauma and acute care surgery2012
Impact of prehospital mode of transport after severe injury: a multicenter evaluation from the Resuscitation Outcomes Consortium.
Trial report in The journal of trauma and acute care surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02440373 (Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Transport and destination hospital for patients with suspected multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Pooled it
- Helicopter EMS for scene response to head-injured patients: systematic review & meta-analysis.BMC emergency medicine · 2025Pooled it
- Survival and cost-effectiveness of helicopter versus ground emergency medical services: a systematic review and meta-analysis with meta-regression and trial sequential analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Pooled it
- Helicopter emergency medical services for adults with major trauma.The Cochrane database of systematic reviews · 2015Pooled it
- Glasgow Outcome Scale Measures and Impact on Analysis and Results of a Randomized Clinical Trial of Severe Traumatic Brain Injury.Journal of neurotrauma · 2019Trial
- Trends in Varying Modes of Hospital Arrival: What Determines the Ideal Mode of Transportation?Cureus · 2025Article
- Mortality rates in Norwegian HEMS-a retrospective analysis from Central Norway.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- High-risk diagnosis combinations in patients undergoing interhospital transfer: a retrospective observational study.BMC emergency medicine · 2022Observational
- Transport of the patient with trauma: a narrative review.Anaesthesia · 2022Review
- Air Rescue for Pediatric Trauma in a Metropolitan Region of Brazil: Profiles, Outcomes, and Overtriage Rates.Frontiers in pediatrics · 2022Article
- Transferred Patients by Fars Province's Helicopter Emergency Medical Service (HEMS); A 2-Years Cross-Sectional Study in Southern Iran.Bulletin of emergency and trauma · 2021Article
- A scoping review of worldwide studies evaluating the effects of prehospital time on trauma outcomes.International journal of emergency medicine · 2020Article
- Making sense of gut feelings in the traumatic brain injury pathogenesis.Neuroscience and biobehavioral reviews · 2019Review
- Defining geographic emergency medical services coverage in trauma systems.The journal of trauma and acute care surgery · 2019Article
- Applying Supervised Machine Learning to Identify Which Patient Characteristics Identify the Highest Rates of Mortality Post-Interhospital Transfer.Biomedical informatics insights · 2019Article
- Comparing population and incident data for optimal air ambulance base locations in Norway.Scandinavian journal of trauma, resuscitation and emergency medicine · 2018Article
- Predictive accuracy of medical transport information for in-hospital mortality.Journal of critical care · 2018Article
- Epidemiological comparison between the Navarra Major Trauma Registry and the German Trauma Registry (TR-DGU®).Scandinavian journal of trauma, resuscitation and emergency medicine · 2017Article
- Multicenter observational prehospital resuscitation on helicopter study.The journal of trauma and acute care surgery · 2017Observational
- Exploring optimal air ambulance base locations in Norway using advanced mathematical modelling.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2017Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundThere is ongoing controversy about the relative effectiveness of air medical versus ground transportation for severely injured patients. In some systems, air medical crews may provide a higher level of care but may require longer transport times. We sought to evaluate the impact of mode of transport on outcome based on analysis of data from two randomized trials of prehospital hypertonic resuscitation.
methodsInjured patients were enrolled based on prehospital evidence of hypovolemic shock (systolic blood pressure ≤70 mm Hg or systolic blood pressure = 71-90 mm Hg with heart rate ≥108 bpm) or severe traumatic brain injury (TBI; Glasgow Coma Scale score ≤8). Patient demographics, injury severity, and physiology were compared based on mode of transport. Multivariate logistic regression was used to determine the impact of mode of transport on 24-hour and 28-day survival for all patients and 6-month extended Glasgow Outcome Scale for patients with TBI, adjusting for differences in injury severity.
resultsIncluded were 2,049 patients, of which 703 (34%) were transported by air. Patients transported by air were more severely injured (mean Injury Severity Score, 30.3 vs. 22.8; p < 0.001), more likely to be in the TBI cohort (70% vs. 55.4%; p < 0.001), and more likely blunt mechanism (94.0% vs. 78.1%; p < 0.001). Patients transported by air had higher rates of prehospital intubation (81% vs. 36%; p < 0.001), received more intravenous fluids (mean 1.3 L vs. 0.8 L; p < 0.001), and had longer prehospital times (mean 76.1 minutes vs. 43.5 minutes; p < 0.001). Adjusted analysis revealed no significant impact of mode of transport on survival or 6-month neurologic outcome (air transport-28-day survival: odds ratio, 1.11; 95% confidence interval, 0.82-1.51; 6-month extended Glasgow Outcome Scale score ≤4: odds ratio, 0.94; 95% confidence interval, 0.68-1.31).
conclusionThere was no difference in the adjusted clinical outcome according to mode of transport. However, air medical transported more severely injured patients with more advanced life support procedures and longer prehospital time. LEVEL OF EVIDENCE: III.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.