Evidence map›Paper›PMID 22491451›Full record

ArticleJournal of virology2012

Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection.

Basel T Assaf, Keith G Mansfield, Susan V Westmoreland, Amitinder Kaur, Kristie L Oxford, Don J Diamond, Peter A Barry

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Human cytomegalovirus-vectored vaccines against HIV.Current opinion in HIV and AIDS · 2019
    Review
  6. Article
  7. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Basel T AssafCenter for Comparative Medicine, University of California, Davis, Davis, California, USA.
Keith G Mansfield
Susan V Westmoreland
Amitinder Kaur
Kristie L Oxford
Don J Diamond
Peter A Barry
Harvard University · USNew England Biolabs (United States) · USUniversity of California, Davis · USCity Of Hope National Medical Center · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
ZETA CHAIN OF T CELL RECEPTOR INTERACTS W/ NEF OF SIV &HIV2P51RR000168 · NCRR · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WESTMORELAND, SUSAN V. · 1985 to 2011
$139.3M
Evaluation of Protective CMV Vaccines in Rhesus MacaquesR01AI063356 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI BARRY, PETER A, DIAMOND, DON J · 2005 to 2014
$4.6M
VETERINARY AND COMPARATIVE PATHOLOGYT32RR007000 · NCRR · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WESTMORELAND, SUSAN V. · 1985 to 2011
$2.8M
MOUSE MODELS OF CANCER, BONE DISEASE, AND LACTATIONK26RR000168 · NCRR · OHIO STATE UNIVERSITY · PI ROSOL, THOMAS J · 2000 to 2004
$547k
NCRR NIH HHS K26 RR000168NCRR NIH HHS P51 RR000168NCRR NIH HHS RR00168NCRR NIH HHS RR07000NCRR NIH HHS T32 RR007000NIAID NIH HHS AI063356NIAID NIH HHS R01 AI063356NIH HHS P51 OD011104NIH HHS P51 OD011107
6 · The paper itself

Abstract

We previously reported that long-term rhesus cytomegalovirus (RhCMV) excretion in infected macaques was related to UL/b' coding content. Acute biopsy specimens of the inoculation sites from the previous study have now been analyzed to determine whether there were acute phenotypic predictors of long-term RhCMV infection. Only in animals displaying acute endothelial tropism and neutrophilic inflammation was RhCMV excretion detected. The results imply that vaccinating against these early viral determinants would significantly impede long-term RhCMV infection.

Indexed as

AnimalsChronic DiseaseCytomegalovirusCytomegalovirus InfectionsEndothelial CellsMacacaNeutrophilsPrimate Diseases

Identifiers

PMID22491451
PMCPMC3372188
OpenAlexW2002725288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.