Evidence map›Paper›PMID 22490672›Full record

ReviewNutrition journal2012

Gut-central nervous system axis is a target for nutritional therapies.

Gustavo D Pimentel, Thayana O Micheletti, Fernanda Pace, José C Rosa, Ronaldo V T Santos, Fabio S Lira

Open access · goldAbstract readReview
In one paragraph

Review in Nutrition journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  15. Biomarkers of Alzheimer's disease among Mexican Americans.Journal of Alzheimer's disease : JAD · 2013
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Gustavo D PimentelDepartment of Internal Medicine, State University of Campinas, Campinas, Brazil. gupimentel@yahoo.com.br
Thayana O Micheletti
Fernanda Pace
José C Rosa
Ronaldo V T Santos
Fabio S Lira
Universidade Estadual de Campinas (UNICAMP) · BRCentro Universitário do Espírito Santo · BRUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, in the 1950s, the chemist Linus Pauling established a relationship between decreased longevity and obesity. At this time, with the advent of studies involving the mechanisms that modulate appetite control, some researchers observed that the hypothalamus is the "appetite centre" and that peripheral tissues have important roles in the modulation of gut inflammatory processes and levels of hormones that control food intake. Likewise, the advances of physiological and molecular mechanisms for patients with obesity, type 2 diabetes mellitus, inflammatory bowel diseases, bariatric surgery and anorexia-associated diseases has been greatly appreciated by nutritionists. Therefore, this review highlights the relationship between the gut-central nervous system axis and targets for nutritional therapies.

Indexed as

Appetite RegulationBariatric SurgeryCentral Nervous SystemDiabetes Mellitus, Type 2DietGastrointestinal HormonesGastrointestinal TractHumansInflammatory Bowel DiseasesMetagenomeObesityPostprandial PeriodGastrointestinal Hormones

Identifiers

PMID22490672
PMCPMC3342925
OpenAlexW2103590783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.