Evidence map›Paper›PMID 22489884›Full record

ReviewBioscience reports2012

Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6.

Jae-Joon Jung, Shivangi M Inamdar, Ajit Tiwari, Amit Choudhury

Open access · hybridAbstract readReview
In one paragraph

Review in Bioscience reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. DNA methylation as a contributor to dysregulation ofbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Role of Ca²⁺ in Inhibiting Ischemia-Induced Apoptosis of Parathyroid Gland Cells in New Zealand White Rabbits.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  13. Article
  14. Article
  15. SNARE-Mediated Exocytosis in Neuronal Development.Frontiers in molecular neuroscience · 2020
    Review
  16. Article
  17. Article
  18. Review
  19. Plasma membrane cholesterol trafficking in steroidogenesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jae-Joon JungDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA.
Shivangi M Inamdar
Ajit Tiwari
Amit Choudhury
University of Iowa · US

Funding

Role of Syntaxin 6 Regulated Post-Golgi Trafficking in AngiogenesisR01HL089599 · NHLBI · UNIVERSITY OF IOWA · PI CHOUDHURY, AMIT · 2008 to 2012
$1.9M
NHLBI NIH HHS HL089599
6 · The paper itself

Abstract

Intracellular membrane trafficking along endocytic and secretory transport pathways plays a critical role in diverse cellular functions including both developmental and pathological processes. Briefly, proteins and lipids destined for transport to distinct locations are collectively assembled into vesicles and delivered to their target site by vesicular fusion. SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein receptor) proteins are required for these events, during which v-SNAREs (vesicle SNAREs) interact with t-SNAREs (target SNAREs) to allow transfer of cargo from donor vesicle to target membrane. Recently, the t-SNARE family member, syntaxin-6, has been shown to play an important role in the transport of proteins that are key to diverse cellular dynamic processes. In this paper, we briefly discuss the specific role of SNAREs in various mammalian cell types and comprehensively review the various roles of the Golgi- and endosome-localized t-SNARE, syntaxin-6, in membrane trafficking during physiological as well as pathological conditions.

Indexed as

AnimalsEndocytosisEndothelial CellsHumansIntracellular MembranesProtein TransportQa-SNARE ProteinsSecretory VesiclesSNARE ProteinsQa-SNARE ProteinsSNARE Proteins

Identifiers

PMID22489884
PMCPMC3392101
OpenAlexW2118089288

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.