Evidence map›Paper›PMID 22488769›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Replication of N2,3-ethenoguanine by DNA polymerases.

Linlin Zhao, Plamen P Christov, Ivan D Kozekov, Matthew G Pence, Pradeep S Pallan, Carmelo J Rizzo, Martin Egli, F Peter Guengerich

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Review
  5. Pyrimido[1,2-Chemistry of heterocyclic compounds · 2021
    Article
  6. Article
  7. Article
  8. The abundant DNA adductThe Journal of biological chemistry · 2019
    Article
  9. Article
  10. Mismodeled purines: implicit alternates and hidden Hoogsteens.Acta crystallographica. Section D, Structural biology · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linlin ZhaoDepartment of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.
Plamen P Christov
Ivan D Kozekov
Matthew G Pence
Pradeep S Pallan
Carmelo J Rizzo
Martin Egli
F Peter Guengerich

Funding

Structural Biology Facility CoreP30ES000267 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 1985 to 2014
$20.3M
TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007028 · NIEHS · VANDERBILT UNIVERSITY · PI F PETER Guengerich, Fiona Edith Harrison · 1985 to 2026
$15.7M
SYNTHETIC APPROACHES TO PAH-ADDUCTED NUCLEOTIDESP01ES005355 · NIEHS · VANDERBILT UNIVERSITY · PI LLOYD, STEPHEN CARROLL · 1991 to 2010
$13.4M
BIOACTIVATION OF HALOGENATED HYDROCARBONSR01ES010546 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2001 to 2020
$8.1M
POLYMERASE INTERACTIONS WITH CARCINOGEN MODIFIED DNAR01ES010375 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2000 to 2014
$5.9M
NIEHS NIH HHS P01 ES005355NIEHS NIH HHS P01 ES05355NIEHS NIH HHS P30 ES000267NIEHS NIH HHS R01 ES010375NIEHS NIH HHS R01 ES010546NIEHS NIH HHS T32 ES007028
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA ReplicationDNA AdductsDNA-Directed DNA PolymeraseGuanineHumansMutationOxidative StressProtein ConformationVinyl ChlorideDNA AdductsDNA-Directed DNA PolymeraseGuanineN(2),3-ethenoguanineVinyl Chloride

Identifiers

PMID22488769
PMCPMC3671877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.