Evidence map›Paper›PMID 22488160›Full record

ArticleNeurotoxicity research2013

Seafood consumption and blood mercury concentrations in Jamaican children with and without autism spectrum disorders.

Mohammad H Rahbar, Maureen Samms-Vaughan, Katherine A Loveland, Manouchehr Ardjomand-Hessabi, Zhongxue Chen, Jan Bressler, Sydonnie Shakespeare-Pellington, Megan L Grove, Kari Bloom, Deborah A Pearson and 2 more

Abstract readComparative Study
In one paragraph

Article in Neurotoxicity research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  15. Associations of Metabolic Genes (International journal of environmental research and public health · 2021
    Article
  16. Correlation between concentrations of four heavy metals in cord blood and childhood blood of Jamaican children.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mohammad H RahbarDivision of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health at Houston, Houston, TX 77030, USA. Mohammad.H.Rahbar@uth.tmc.edu
Maureen Samms-Vaughan
Katherine A Loveland
Manouchehr Ardjomand-Hessabi
Zhongxue Chen
Jan Bressler
Sydonnie Shakespeare-Pellington
Megan L Grove
Kari Bloom
Deborah A Pearson
Gerald C Lalor
Eric Boerwinkle
The University of Texas Health Science Center at Houston · USThe University of Texas Health Science Center · USUniversity of the West Indies · JMUniversity of the West Indies System · JM

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Epidemiological Research on Autism in Jamaica - Phase IIR01ES022165 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2013 to 2018
$2.8M
Epidemiological Research on Autism in JamaicaR21HD057808 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2009 to 2010
$278k
NCATS NIH HHS UL1 TR000371NCATS NIH HHS UL1 TR003167NCRR NIH HHS UL1 RR024148NICHD NIH HHS R21 HD057808NICHD NIH HHS R21HD057808NIEHS NIH HHS R01 ES022165
6 · The paper itself

Abstract

Mercury is a toxic metal shown to have harmful effects on human health. Several studies have reported high blood mercury concentrations as a risk factor for autism spectrum disorders (ASDs), while other studies have reported no such association. The goal of this study was to investigate the association between blood mercury concentrations in children and ASDs. Moreover, we investigated the role of seafood consumption in relation to blood mercury concentrations in Jamaican children. Based on data for 65 sex- and age-matched pairs (2-8 years), we used a General Linear Model to test whether there is an association between blood mercury concentrations and ASDs. After controlling for the child's frequency of seafood consumption, maternal age, and parental education, we did not find a significant difference (P = 0.61) between blood mercury concentrations and ASDs. However, in both cases and control groups, children who ate certain types of seafood (i.e., salt water fish, sardine, or mackerel fish) had significantly higher (all P < 0.05) geometric means blood mercury concentration which were about 3.5 times that of children living in the US or Canada. Our findings also indicate that Jamaican children with parents who both had education up to high school are at a higher risk of exposure to mercury compared to children with at least one parent who had education beyond high school. Based on our findings, we recommend additional education to Jamaican parents regarding potential hazards of elevated blood mercury concentrations, and its association with seafood consumption and type of seafood.

Indexed as

SeafoodAdultAge FactorsAnimalsBiomarkersCase-Control StudiesChildChild Development Disorders, PervasiveChild, PreschoolFemaleHumansJamaicaMaleMercurySocioeconomic FactorsSurveys and QuestionnairesBiomarkersMercury

Identifiers

PMID22488160
PMCPMC3969434
OpenAlexW1967578162

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.