Evidence map›Paper›PMID 22488012›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2013

Platelet-rich plasma: does it help reduce tunnel widening after ACL reconstruction?

Antonio Vadalà, Raffaele Iorio, Angelo De Carli, Matteo Ferretti, Daniele Paravani, Ludovico Caperna, Carlo Iorio, Andrea Gatti, Andrea Ferretti

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  7. PRP does not improve the objective outcomes of anterior cruciate ligament reconstruction: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Pooled it
  8. Platelet-rich therapies for musculoskeletal soft tissue injuries.The Cochrane database of systematic reviews · 2014
    Pooled it
  9. Review
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  19. Current trends in the anterior cruciate ligament part 1: biology and biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio VadalàOrthopaedic Unit and Kirk Kilgour Sports Injury Centre, S. Andrea Hospital, University of Rome La Sapienza, Via Grottarossa, 1035, Rome, Italy. anto.vada@libero.it
Raffaele Iorio
Angelo De Carli
Matteo Ferretti
Daniele Paravani
Ludovico Caperna
Carlo Iorio
Andrea Gatti
Andrea Ferretti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate the efficacy of platelet-rich plasma (PRP) in reducing femoral and tibial tunnel enlargement in patients operated on for anterior cruciate ligament reconstruction with hamstrings.

methodsForty male patients, in which both femoral and tibial 9-mm tunnels were performed because of the graft size, were enrolled in this prospective study. They were randomly assigned to group A (20 patients, PRP group) and group B (20 patients, control group). All patients were followed up at a median of 14.7 months (range 10-16 months), with a physical examination, the Tegner, Lysholm and objective IKDC scoring scales, and with the KT-1000 arthrometer. Moreover, they underwent a CT evaluation in order to assess the amount of tunnel enlargement.

resultsFemoral tunnel diameter increased from 9.0 ± 0.1 mm to 9.8 ± 0.3 mm in group A (p = 0.032) and from 9.0 ± 0.1 mm to 9.4 ± 0.5 mm in group B (p = 0.043). Tibial tunnel diameter increased from 9.0 ± 0.2 mm to 10.9 ± 0.2 mm in group A (p = 0.029) and from 9.1 ± 0.1 mm to 10.1 ± 0.4 mm in group B (p = 0.028). Physical examination as well as the evaluation scales used showed no differences between the two groups.

conclusionsThe use of PRP does not seem to be effective in preventing tunnel enlargement.

Indexed as

Anterior Cruciate Ligament InjuriesPlatelet-Rich PlasmaAdolescentAdultAnterior Cruciate LigamentFemurHumansJoint InstabilityMaleMiddle AgedMultidetector Computed TomographyTendonsTibiaYoung Adult

Identifiers

PMID22488012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.