ReviewCurrent opinion in neurology2012
Migraine changes the brain: neuroimaging makes its mark.
Review in Current opinion in neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- Assessment of cognitive dysfunction during migraine attacks: a systematic review.Journal of neurology · 2015Pooled it
- Headache and non-headache symptoms provoked by nitroglycerin in migraineurs: A human pharmacological triggering study.Cephalalgia : an international journal of headache · 2020Trial
- White matter tract microstructure of the mPFC-amygdala predicts interindividual differences in placebo response related to treatment in migraine patients.Human brain mapping · 2019Trial
- Transcranial Direct Current Stimulation (tDCS) of the visual cortex: a proof-of-concept study based on interictal electrophysiological abnormalities in migraine.The journal of headache and pain · 2013Trial
- Kinematic analysis of multisensory integration and sensory load induced fatigue in migraine.Scientific reports · 2026Article
- Temporal Changes in Affective Symptoms, Headache Burden, and Quality of Life Following rTMS Treatment in Migraine: A Longitudinal Study.Healthcare (Basel, Switzerland) · 2026Article
- Mechanistic approach and therapeutic strategies in menstrual and non-menstrual migraine.Future science OA · 2025Review
- Bridging migraine and psychosis: a neuropsychiatric review of shared dopaminergic mechanisms.Frontiers in neurology · 2025Review
- Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery.BMC neurology · 2024Article
- Modulation of temporal and occipital cortex by acupuncture in non-menstrual MWoA patients: a rest BOLD fMRI study.BMC complementary medicine and therapies · 2024Article
- Central Mechanism of Acupuncture Treatment in Patients with Migraine: Study Protocol for Randomized Controlled Neuroimaging Trial.Journal of pain research · 2023Article
- Migraine: interactions between brain's trait and state.CNS spectrums · 2022Review
- Neurological mechanism and treatment effects prediction of acupuncture on migraine without aura: Study protocol for a randomized controlled trial.Frontiers in neurology · 2022Article
- A Pilot Mitochondrial Genome-Wide Association on Migraine Among Saudi Arabians.International journal of general medicine · 2022Article
- Aberrant Modulations of Neurocognitive Network Dynamics in Migraine Comorbid With Tinnitus.Frontiers in aging neuroscience · 2022Article
- Parenchymal neuroinflammatory signaling and dural neurogenic inflammation in migraine.The journal of headache and pain · 2021Review
- Structural and Functional Brain Changes in Migraine.Pain and therapy · 2021Review
- Distinct Activity of Endocannabinoid-Hydrolyzing Enzymes MAGL and FAAH in Key Regions of Peripheral and Central Nervous System Implicated in Migraine.International journal of molecular sciences · 2021Article
- Brain Imaging Biomarkers for Chronic Pain.Frontiers in neurology · 2021Review
- Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia.PloS one · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
purpose of reviewThis review summarizes key findings of the current literature on functional neuroimaging in migraine and describes how these studies have changed our view of the disorder. RECENT
findingsRecent studies have started not only to investigate the global cerebral activation pattern during migraine attacks, but to address specific aspects of migraine attacks such as photophobia, osmophobia as well as pain perception with the aim of disentangling the underlying mechanisms. There is also more and more evidence that the migraine brain is abnormal even outside of attacks and that repeated attacks are leading to functional and structural alterations in the brain, which may in turn drive the transformation of migraine to its chronic form. Some new results are pinpointing toward a potential role of interesting new brain areas in migraine pathophysiology such as the temporal cortex or the basal ganglia. SUMMARY: Neuroimaging studies are beginning to shed light on the mechanisms underlying the development and evolution of migraine and its specific symptoms. Future studies have the potential to also improve our understanding of established and upcoming treatment approaches and to monitor treatment effects in an objective and noninvasive way.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.