ReviewCurrent opinion in neurobiology2012
OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease.
Review in Current opinion in neurobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 131 citations in OpenAlex.
- Article
- The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem Cells.Stem cells and development · 2025Article
- Mechanisms of brain overgrowth in autism spectrum disorder with macrocephaly.Frontiers in neuroscience · 2025Review
- Human stem cell models to unravel brain cancer.BMC cancer · 2024Review
- Indirect neurogenesis in space and time.Nature reviews. Neuroscience · 2024Review
- Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development.Nature communications · 2024Article
- Review
- NeuroTri2-VISDOT: An open-access tool to harness the power of second trimester human single cell data to inform models of Mendelian neurodevelopmental disorders.bioRxiv : the preprint server for biology · 2024Article
- Glutaminolysis and the Control of Neural Progenitors in Neocortical Development and Evolution.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023Review
- The SVZ stem cell niche-components, functions, andFrontiers in cell and developmental biology · 2023Review
- Evolution of central neural circuits: state of the art and perspectives.Nature reviews. Neuroscience · 2022Review
- Differential age-dependent development of inter-area brain connectivity in term and preterm neonates.Pediatric research · 2022Article
- Neurogenesis and Viral Infection.Frontiers in immunology · 2022Review
- Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Length of the Neurogenic Period-A Key Determinant for the Generation of Upper-Layer Neurons During Neocortex Development and Evolution.Frontiers in cell and developmental biology · 2021Review
- Brain Disorders and Chemical Pollutants: A Gap Junction Link?Biomolecules · 2020Review
- An integrative understanding of comparative cognition: lessons from human brain evolution.Integrative and comparative biology · 2020Review
- Brain Organoids: Human Neurodevelopment in a Dish.Cold Spring Harbor perspectives in biology · 2020Review
- Invited Review: Epigenetics in neurodevelopment.Neuropathology and applied neurobiology · 2020Review
- Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex.eLife · 2019Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Recent discoveries concerning the architecture and cellular dynamics of the developing human brain are revealing new differences between mouse and human cortical development. In mice, neurons are produced by ventricular radial glial (RG) cells and subventricular zone intermediate progenitor (IP) cells. In the human cortex, both ventricular RG and highly motile outer RG cells generate IP cells, which undergo multiple rounds of transit amplification in the outer subventricular zone before producing neurons. This creates a more complex environment for neurogenesis and neuronal migration, adding new arenas in which neurodevelopmental disease gene mutation could disrupt corticogenesis. A more complete understanding of disease mechanisms will involve use of emerging model systems with developmental programs more similar to that of the human neocortex.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.