Evidence map›Paper›PMID 22486486›Full record

ReviewJournal of child psychology and psychiatry, and allied disciplines2012

Annual research review: re-thinking the classification of autism spectrum disorders.

Catherine Lord, Rebecca M Jones

Abstract readReview
In one paragraph

Review in Journal of child psychology and psychiatry, and allied disciplines, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Music therapy for people with autism spectrum disorder.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Recognition of emotions in autism: a formal meta-analysis.Journal of autism and developmental disorders · 2013
    Pooled it
  5. Associations Between Autism and Self-Reported Dimensions of Interoception.Autism : the international journal of research and practice · 2026
    Article
  6. Article
  7. Case Report: A novelFrontiers in psychiatry · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Autism severity and its relationship to disability.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  18. Article
  19. Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Catherine LordCenter for Autism and the Developing Brain, Weill-Cornell Medical College and New York Presbyterian Hospital/Westchester Division, White Plains, NY, USA.
Rebecca M Jones

Funding

A Multi-Site Randomized Study of Intensive Treatment for Toddlers with AutismR01MH081757 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ROGERS, SALLY J · 2007 to 2011
$14.8M
2/2-Effects of Parent-Implemented Intervention for Toddlers with Autism SpectrumR01MH078165 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORD, CATHERINE · 2008 to 2012
$4.0M
Longitudinal Studies of Autism Spectrum Disorders: 2 to 23R01MH081873 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORD, CATHERINE · 2008 to 2012
$2.7M
Development of a Brief Screener for Research in Autism Spectrum DisordersRC1MH089721 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONK, CHRISTOPHER STEPHEN · 2009 to 2010
$997k
NIMH NIH HHS MH078165NIMH NIH HHS MH 081757NIMH NIH HHS MH 081873NIMH NIH HHS MH 089721NIMH NIH HHS R01 MH078165NIMH NIH HHS R01 MH081757NIMH NIH HHS R01 MH081873NIMH NIH HHS RC1 MH089721PHS HHS UA3-MC-1055
6 · The paper itself

Abstract

backgroundThe nosology of autism spectrum disorders (ASD) is at a critical point in history as the field seeks to better define dimensions of social-communication deficits and restricted/repetitive behaviors on an individual level for both clinical and neurobiological purposes. These different dimensions also suggest an increasing need for quantitative measures that accurately map their differences, independent of developmental factors such as age, language level and IQ.

methodPsychometric measures, clinical observation as well as genetic, neurobiological and physiological research from toddlers, children and adults with ASD are reviewed.

resultsThe question of how to conceptualize ASDs along dimensions versus categories is discussed within the nosology of autism and the proposed changes to the DSM-5 and ICD-11. Differences across development are incorporated into the new classification frameworks.

conclusionsIt is crucial to balance the needs of clinical practice in ASD diagnostic systems, with neurobiologically based theories that address the associations between social-communication and restricted/repetitive dimensions in individuals. Clarifying terminology, improving description of the core features of ASD and other dimensions that interact with them and providing more valid and reliable ways to quantify them, both for research and clinical purposes, will move forward both practice and science.

Indexed as

Child Development Disorders, PervasiveAdultChildChild, PreschoolChild PsychiatryDiagnostic and Statistical Manual of Mental DisordersHumansInternational Classification of DiseasesPsychometrics

Identifiers

PMID22486486
PMCPMC3446247

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.