Evidence map›Paper›PMID 22485011›Full record

ReviewJournal of epidemiology2012

Coronary artery calcification by computed tomography in epidemiologic research and cardiovascular disease prevention.

Akira Sekikawa, J David Curb, Daniel Edmundowicz, Tomonori Okamura, Jina Choo, Akira Fujiyoshi, Kamal Masaki, Katsuyuki Miura, Lewis H Kuller, Chol Shin and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Lung Cancer Screening, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Akira SekikawaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15213, USA. akira@pitt.edu
J David Curb
Daniel Edmundowicz
Tomonori Okamura
Jina Choo
Akira Fujiyoshi
Kamal Masaki
Katsuyuki Miura
Lewis H Kuller
Chol Shin
Hirotsugu Ueshima
Shiga University of Medical Science · JPKorea University · KRUniversity of Hawaiʻi at Mānoa · USUniversity of Pittsburgh · USKeio University · JPUniversity of Pittsburgh Medical Center · US

Funding

Foreign CohortR01HL068200 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEKIKAWA, AKIRA · 2003 to 2012
$5.6M
Epidemiology of CHD of Men Aged 40+ in US, Hawaii, JapanR01HL071561 · NHLBI · PACIFIC HEALTH RESEARCH INSTITUTE · PI CURB, JESS DAVID · 2003 to 2006
$1.7M
NHLBI NIH HHS HL071561NHLBI NIH HHS HL68200NHLBI NIH HHS R01 HL068200NHLBI NIH HHS R01 HL071561
6 · The paper itself

Abstract

Both American and European guidelines recommend coronary artery calcification (CAC) as a tool for screening asymptomatic individuals at intermediate risk for coronary heart disease (CHD). These recommendations are based on epidemiologic studies mostly in the United States. We review (1) the use of CAC in primary prevention of CHD in the United States, (2) epidemiologic studies of CAC in asymptomatic adults outside of the United States, and (3) international epidemiologic studies of CAC. This review will not consider clinical studies of CAC among patients or symptomatic individuals. US studies have shown that CAC is a strong independent predictor of CHD in both sexes among middle-aged and old age groups, various ethnic groups, and individuals with and without diabetes and that CAC plays an important role in reclassifying individuals from intermediate to high risk. Studies in Europe support these conclusions. The Electron-Beam Tomography, Risk Factor Assessment Among Japanese and US Men in the Post-World-War-II birth cohort (ERA JUMP) Study is the first international study to compare subclinical atherosclerosis, including CAC among Japanese, Japanese Americans, Koreans, and whites. It showed that as compared with whites, Japanese had lower levels of atherosclerosis, whereas Japanese Americans had similar or higher levels. CAC is being increasingly used as a screening tool for asymptomatic individuals in Europe and the United States. CAC is a powerful research tool, because it enables us to describe differences in atherosclerotic burden across populations. Such research could identify factors responsible for differences among populations, which may improve CHD prevention.

Indexed as

Coronary Artery DiseaseCoronary DiseaseEpidemiologic StudiesHumansPrimary PreventionRisk AssessmentTomography, X-Ray ComputedUnited StatesVascular Calcification

Identifiers

PMID22485011
PMCPMC3362675
OpenAlexW2117510300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.